Goat’s milk
Goat’s milk Scientific Information
Type: Whole Allergen
Display Name: Goat's milk
Allergen code: f300
Other Names: Goat's milk
WHO/ICD-11 code: XM4Y68
Route Of Exposure
Main
Goat's milk, cheese and other dairy products.
Clinical Relevance
IgE-mediated reactions
IgE-mediated reactions have been reported.
Other topic
Goat’s milk often appears as a substitute for cow’s milk, particularly in diets administered by parents to children with atopic dermatitis. Some cow’s milk-allergic children may tolerate goat’s milk. However, there appears to be evidence for crossreactivity between goat’s milk and cow’s milk. In a study of crossreactivity of the casein fractions among different species, the IgE response to ewe and goat’s milk was weaker than that to cow and buffalo.
14/16 patients with cow’s milk allergy had specific IgE antibodies to goat’s milk. Serum albumin and caseins show homology to the corresponding proteins of cow and sheep.
Cross-Reactivity
Milk from related animals
References
- Webber, SA; Graham-Brown, RAC; Hutchinson, PE; Burns, DA. Dietary manipulation in childhood atopic dermatitis. Br J Dermatol; 1989; 121: 91-98.
- Ellis, MH; Short, J; Heiner, DC. Anaphylaxis after ingestion of a recently introduced hydrolyzed whey protein formula. J Pediatr; 1991; 118: 74-77.
- Gjesing, B; Østerballe, O; Schwartz, B; Wahn, U; Løwenstein, H. Allergen-specific IgE antibodies against antigenic components in cow milk and milk substitutes. Allergy; 1986; 41: 51-56.
- Bernard, H; Wal, JM; Creminon, C; Grassi, J; Yvon, M; Houdebine, LM. Sensitivities of cow's milk allergic patients to casein fraction of milks from different species. Allergy; 1992; 47: 306.
- Dean, TP; Adler, BR; Ruge, F; Warner, JO. In vitro allergenicity of cow's milk substitutes. Clin and Exp Allergy; 1993; 23: 205-210.
- Spuergin, P; Walter, M; Schiltz, E; Deichman, K; Forster, J; Mueller. Allergenicity of a -caseins from cow, sheep, and goat. Allergy; 1997; 52: 293-298.