Thyroid Extract
OTHER NAME(S): Desiccated Thyroid, Extracto de tiroides, Extrait de Thyroïde, Extrait Thyroïdien, Extrait Sec de Thyroïde, None., Thyroid, Extracto de Tiroides, Extrait thyroïdien
Overview
Thyroid extract comes from tissue in the animal thyroid gland. Thyroid extract supplements contain dried and/or ground raw tissue or extract from tissue.
There are two major hormones produced by the thyroid gland: triiodothyronine (T3) and thyroxine (T4). Thyroid extract contains both hormones. Both T3 and T4 are involved in the control of growth and development, particularly in the development of the bones and brains of a developing fetus.
People use thyroid extract for low thyroid hormone production (hypothyroidism), infertility, thyroid cancer, and other conditions, but there is no good scientific evidence to support these uses. It might also be unsafe.
Uses
We currently have no information for Thyroid Extract overview.
Side Effects
When taken by mouth: Thyroid extract is possibly unsafe. The strength of the hormones in thyroid extract is not consistent. This makes it difficult to get the right dose each day. Using thyroid extract might cause thyroid hormone levels to rise too much and cause serious side effects.
Precautions
When taken by mouth: Thyroid extract is possibly unsafe. The strength of the hormones in thyroid extract is not consistent. This makes it difficult to get the right dose each day. Using thyroid extract might cause thyroid hormone levels to rise too much and cause serious side effects.
Pregnancy and breast-feeding: There isn't enough reliable information to know if thyroid extract is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Heart conditions: Thyroid extract contains thyroid hormones. High levels of thyroid hormones can stress the heart. This might cause further heart damage in people with heart disease.
Elderly: Thyroid extract contains thyroid hormones. High levels of thyroid hormones can stress the heart. This could result in serious damage in older people who might already have a weakened heart..
High thyroid hormone levels: Thyroid extract contains thyroid hormones. In people who already have high thyroid levels, this could cause even higher levels and more side effects.
Interactions
Moderate Interaction
Be cautious with this combination
- Levothyroxine (Synthroid, Levothroid, Levoxyl, and others) interacts with Thyroid ExtractThyroid extract contains thyroid hormones. Levothyroxine is used to increase thyroid hormone levels in people whose levels are too low. Taking thyroid extract with levothyroxine might increase the effects and side effects of levothyroxine.
Dosing
There isn't enough reliable information to know what an appropriate dose of thyroid extract might be. Thyroid extract might also be unsafe. The strength of the hormones found in thyroid extract is not consistent. Speak with a healthcare provider before use.
References
- Naficy, H. and Behjatnia, Y. The effect of thyroid extract on luteal phase deficiency. Acta Med Iran 1975;18(1-2):55-60.
- Benvenga, S., Trimarchi, F., Barbera, C., Costante, G., Morabito, S., Barberio, G., and Consolo, F. Circulating immunoglobulin E (IgE) antibodies to L-thyroxine in a euthyroid patient with multinodular goiter and allergic rhinitis. J Endocrinol Invest 1984;7(1):47-50.
- Gerard, P., Malvaux, P., and De Visscher, M. Accidental poisoning with thyroid extract treated by exchange transfusion. Arch Dis Child 1972;47(256):981-982.
- Tofahrn, J. and Hundeiker, M. [Nevus eruption following thyroidin with spontaneous involution]. Z Hautkr 1976;51(15):617-620.
- Rees-Jones RW, Larsen PR. Triiodothyronine and thyroxine content of desiccated thyroid tablets. Metabolism 1977;26(11):1213-1218.
- No authors listed. Thyroid extract. Br Med J 1978;2(6131):200.
- No authors listed. Thyroid extract. Br Med J 1978;2(6133):354.
- Mangieri CN, Lund MH. Potency of United States Pharmacopeia dessicated thyroid tablets as determined by the antigoitrogenic assay in rats. J Clin Endocrinol Metab 1970;30(1):102-4.
- Goodpasture EW. The influence of thyroid products on the production of myocardial necrosis. J Exp Med 1921;34(4):407-423.
- Cooper DS. Thyroid hormone treatment: new insights into an old therapy. JAMA 1989;261:2694-2695.
- Jackson IM, Cobb WE. Why does anyone still use desiccated thyroid USP? Am J Med 1978;64(2):284-8.
- Clarke N. Kabadi UM. Optimizing treatment of hypothyroidism. Treat Endocrinol 2004;3(4):217-221.
- Tata JR. Looking for the mechanism of action of thyroid hormone. J Thyroid Res 2011;2011:730630.
- Jha S, Waghdhare S, Reddi R, Bhattacharya P. Thyroid storm due to inappropriate administration of a compounded thyroid hormone preparation successfully treated with plasmapheresis. Thyroid. 2012;22(12):1283-6.
- Ponder M, Lamos E, Munir K. Two cases of Armour thyroid interference in thyroglobulin monitoring for thyroid cancer. Case Rep Endocrinol 2021;2021:1152572.
- Pawar RS, Sagi S, Leontyev D. Determination of thyroid hormones in dietary supplements using liquid chromatography-tandem mass spectrometry. Drug Test Anal 2022;14(3):578-586.