Red Raspberry
OTHER NAME(S): Framboise, Framboise Rouge, Framboisier Rouge, Framboisier Sauvage, Frambuesa Roja, Raspberry, Rubi Idaei Folium, Rubus, Rubus idaeus, Rubus buschii, Rubus strigosus, Raspberry leaf, RED RASPBERRY LEAF, Frambuesa roja, Framboisier rouge
Overview
Red raspberry (Rubus idaeus) plant produces the widely eaten, sweet fruit. Red raspberry fruit and leaf have been used as medicine for centuries.
The chemicals in red raspberry might have antioxidant effects and help relax blood vessels. They might also cause muscles to contract or relax, depending on the dose and the muscle involved. This is the theory behind red raspberry's use in easing labor and delivery.
People use red raspberry for labor, diarrhea, diabetes, and many other purposes, but there is no good scientific evidence to support these uses.
Don't confuse red raspberry with black raspberry, blackberry, or raspberry ketone.
Uses
We currently have no information for Red Raspberry overview.
Side Effects
When taken by mouth: Red raspberry fruit is commonly consumed as a food. It is possibly safe when taken in larger amounts as medicine. Red raspberry fruit is usually well-tolerated. There isn't enough reliable information to know if red raspberry leaf is safe or what the side effects might be.
Precautions
When taken by mouth: Red raspberry fruit is commonly consumed as a food. It is possibly safe when taken in larger amounts as medicine. Red raspberry fruit is usually well-tolerated. There isn't enough reliable information to know if red raspberry leaf is safe or what the side effects might be.
Pregnancy: Red raspberry fruit is commonly consumed as a food. Red raspberry leaf is possibly safe when taken by mouth as medicine during LATE pregnancy under the direct supervision of a healthcare provider. But don't take it on your own. It is likely unsafe to take red raspberry leaf as a medicine earlier in pregnancy. It might act like the hormone estrogen. This might harm the pregnancy.
Breast-feeding: Red raspberry fruit is commonly consumed as a food. There isn't enough reliable information to know if it is safe to take red raspberry leaf when breast-feeding. Stay on the safe side and avoid use.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Red raspberry leaf might act like estrogen. If you have any condition that might be sensitive to estrogen, don't use red raspberry leaf.
Interactions
Moderate Interaction
Be cautious with this combination
- Insulin interacts with Red RaspberryInsulin decreases blood sugar levels in the body. Red raspberry leaf might also decrease blood sugar levels in the body. Taking raspberry leaf along with insulin might cause blood sugar levels in the body to be too low. Monitor your blood sugar closely. The dose of your insulin might need to be changed.
- Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Red RaspberryRed raspberry leaf might slow blood clotting. Taking red raspberry leaf along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Dosing
Red raspberry fruit is commonly eaten on its own and processed into jams and other foods.
As medicine, there isn't enough reliable information to know what an appropriate dose of red raspberry fruit or leaf might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Bamford DS, Percival RC, Tothill AU. Raspberry leaf tea: a new aspect to an old problem. Br J Pharmacol 1970;40:161P-162P.
- McFarlin BL, Gibson MH, O'Rear J, Harman P. A national survey of herbal preparation use by nurse-midwives for labor stimulation. Review of the literature and recommendations for practice. J Nurse Midwifery 1999;44:205-16.
- Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
- Parsons M, Simpson M, Ponton T. Raspberry leaf and its effects on labour: safety and efficacy. Aust Coll Midwives Inc J 1999;12:20-5.
- Simpson M, Parsons M, Greenwood J, Wade K. Raspberry leaf in pregnancy: its safety and efficacy in labor. J Midwifery Womens Health 2001;46:51-9..
- Wada L, Ou B. Antioxidant activity and phenolic content of Oregon caneberries. J Agric Food Chem 2002;50:3495-500..
- Wang SY, Jiao H. Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J Agric Food Chem 2000;48:5677-84..
- Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6..
- Mullen W, McGinn J, Lean ME, et al. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J Agric Food Chem 2002;50:5191-6..
- Morimoto C, Satoh Y, Hara M, et al. Anti-obese action of raspberry ketone. Life Sci 2005;77:194-204. .
- Puupponen-Pimia, R., Nohynek, L., Hartmann-Schmidlin, S., Kahkonen, M., Heinonen, M., Maatta-Riihinen, K., and Oksman-Caldentey, K. M. Berry phenolics selectively inhibit the growth of intestinal pathogens. J Appl Microbiol. 2005;98(4):991-1000.
- de Ancos, B., Ibanez, E., Reglero, G., and Cano, M. P. Frozen storage effects on anthocyanins and volatile compounds of raspberry fruit. J Agric.Food Chem. 2000;48(3):873-879.
- Hakkinen, S. H., Karenlampi, S. O., Mykkanen, H. M., and Torronen, A. R. Influence of domestic processing and storage on flavonol contents in berries. J Agric.Food Chem 2000;48(7):2960-2965.
- Ryan, T., Wilkinson, J. M., and Cavanagh, H. M. Antibacterial activity of raspberry cordial in vitro. Res.Vet.Sci. 2001;71(3):155-159.
- Liu, M., Li, X. Q., Weber, C., Lee, C. Y., Brown, J., and Liu, R. H. Antioxidant and antiproliferative activities of raspberries. J Agric.Food Chem 5-8-2002;50(10):2926-2930.
- Mullen, W., Lean, M. E., and Crozier, A. Rapid characterization of anthocyanins in red raspberry fruit by high-performance liquid chromatography coupled to single quadrupole mass spectrometry. J Chromatogr.A 8-9-2002;966(1-2):63-70.
- Rojas-Vera, J., Patel, A. V., and Dacke, C. G. Relaxant activity of raspberry (Rubus idaeus) leaf extract in guinea-pig ileum in vitro. Phytother.Res. 2002;16(7):665-668.
- Cavanagh, H. M., Hipwell, M., and Wilkinson, J. M. Antibacterial activity of berry fruits used for culinary purposes. J Med Food 2003;6(1):57-61.
- Sherson, D., Andersen, B., Hansen, I., and Kjoller, H. Occupational asthma due to freeze-dried raspberry. Ann Allergy Asthma Immunol. 2003;90(6):660-663.
- Beekwilder, J., Jonker, H., Meesters, P., Hall, R. D., van, der Meer, I, and Ric, de, V. Antioxidants in raspberry: on-line analysis links antioxidant activity to a diversity of individual metabolites. J Agric.Food Chem 5-4-2005;53(9):3313-3320.
- Morillas-Ruiz, J., Zafrilla, P., Almar, M., Cuevas, M. J., Lopez, F. J., Abellan, P., Villegas, J. A., and Gonzalez-Gallego, J. The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: results from a placebo-controlled double-blind study in cyclists. Eur J Appl Physiol 2005;95(5-6):543-549.
- Kowalczyk, E., Krzesinski, P., Fijalkowski, P., Blaszczyk, J., and Kowalski, J. [The use of anthocyanins in the treatment of cardiovascular diseases]. Pol.Merkuriusz.Lek. 2005;19(109):108-110.
- Bagchi, D., Roy, S., Patel, V., He, G., Khanna, S., Ojha, N., Phillips, C., Ghosh, S., Bagchi, M., and Sen, C. K. Safety and whole-body antioxidant potential of a novel anthocyanin-rich formulation of edible berries. Mol.Cell Biochem. 2006;281(1-2):197-209.
- Beekwilder, J., Hall, R. D., and de Vos, C. H. Identification and dietary relevance of antioxidants from raspberry. Biofactors 2005;23(4):197-205.
- Nohynek, L. J., Alakomi, H. L., Kahkonen, M. P., Heinonen, M., Helander, I. M., Oksman-Caldentey, K. M., and Puupponen-Pimia, R. H. Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens. Nutr Cancer 2006;54(1):18-32.
- Carnat, A. P., Pourrat, H., and Pourrat, A. [Antioxydant activity of raspberry seeds oil (author's transl)]. Ann.Pharm.Fr. 1979;37(3-4):119-123.
- Rice-Evans. The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition. Free Radical Research 2002;36(2):217-233.
- Allen CT and Peden-Adams MM. Subchronic Exposure to Ellagic Acid Impairs Cytotoxic T-Cell Function and Supresses Humoral Immunity in Mice. Immunopharmacology & Immunotoxicology 2003;25(3):409.
- Gudej, J. Kaempferol and quercetin glycosides from Rubus idaeus L. Leaves. Acta Poloniae Pharmaceutica - Drug Research (Poland) 2003;60:313-315.
- Cheang KI, Nguyen TT, Karjane NW, Salley KE. Raspberry Leaf and Hypoglycemia in Gestational Diabetes Mellitus. Obstet Gynecol. 2016;128(6):1421-4.
- Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.
- Zhang X, Sandhu A, Edirisinghe I, Burton-Freeman B. An exploratory study of red raspberry (Rubus idaeus L.) (poly)phenols/metabolites in human biological samples. Food Funct 2018;9(2):806-18. doi: 10.1039/c7fo00893g.
- Szymanowska U, Baraniak B, Bogucka-Kocka A. Antioxidant, anti-inflammatory, and postulated cytotoxic activity of phenolic and anthocyanin-rich fractions from Polana raspberry (Rubus idaeus L.) fruit and juice - in vitro study. Molecules 2018;23(7). pii: E1812. doi: 10.3390/molecules23071812.
- Rattanawiwatpong P, Wanitphakdeedecha R, Bumrungpert A, Maiprasert M. Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial. J Cosmet Dermatol 2020;19(3):671-6. doi: 10.1111/jocd.13305.
- Kshatriya D, Li X, Giunta GM, et al. Phenolic-enriched raspberry fruit extract (Rubus idaeus) resulted in lower weight gain, increased ambulatory activity, and elevated hepatic lipoprotein lipase and heme oxygenase-1 expression in male mice fed a high-fat diet. Nutr Res 2019;68:19-33. doi: 10.1016/j.nutres.2019.05.005.
- Zhang X, Sandhu A, Edirisinghe I, Burton-Freeman BM. Plasma and Urinary (Poly)phenolic Profiles after 4-Week Red Raspberry (Rubus idaeus L.) Intake with or without Fructo-Oligosaccharide Supplementation. Molecules. 2020 Oct 17;25(20):4777.
- Franck M, de Toro-Martín J, Garneau V, et al. Effects of Daily Raspberry Consumption on Immune-Metabolic Health in Subjects at Risk of Metabolic Syndrome: A Randomized Controlled Trial. Nutrients. 2020 Dec 17;12(12):3858.
- Bowman R, Taylor J, Muggleton S, Davis D. Biophysical effects, safety and efficacy of raspberry leaf use in pregnancy: a systematic integrative review. BMC Complement Med Ther. 2021;21(1):56.
- Henrotin Y, Cozannet RL, Fança-Berthon P, et al. Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial. BMC Musculoskelet Disord 2022;23(1):650.