Manchurian Thorn
OTHER NAME(S): Angélique du Japon, Aralie Japonaise, Espino de Manchuria, Manchurian Angelica Tree, Mandschurische Aralie, Aralia mandshurica, Aralia elata, Espina De Manchuria, Angélique Du Japon
Overview
Manchurian thorn is a tree. The bark and roots are used to make medicine.
People take Manchurian thorn by mouth as an adaptogen and for obesity, headache, depression, and other conditions, but there is no good scientific evidence to support its use.
There isn't enough information to know how Manchurian thorn might work as a medicine.
There isn't enough information to know how Manchurian thorn might work as a medicine.
Uses
Insufficient Evidence for
- Obesity.
- Tiredness.
- Weakness.
- Headache.
- Depression.
- Stress.
- To improve the immune system.
- Other conditions.
More evidence is needed to rate the effectiveness of Manchurian thorn for these uses.
Side Effects
When taken by mouth: There isn't enough reliable information to know if Manchurian thorn is safe or what the side effects might be.
Precautions
When taken by mouth: There isn't enough reliable information to know if Manchurian thorn is safe or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if Manchurian thorn is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Diabetes: Manchurian thorn might lower blood sugar levels. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use Manchurian thorn.
Liver disease: Manchurian thorn might make liver disease worse.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications for diabetes (Antidiabetes drugs) interacts with Manchurian ThornManchurian thorn might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking Manchurian thorn along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
- Medications that can harm the liver (Hepatotoxic drugs) interacts with Manchurian ThornManchurian thorn might harm the liver. Taking Manchurian thorn along with medication that might also harm the liver can increase the risk of liver damage. Do not take Manchurian thorn if you are taking a medication that can harm the liver. Some medications that can harm the liver include acetaminophen (Tylenol and others), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanox), erythromycin (Erythrocin, Ilosone, others), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), and many others.
Dosing
The appropriate dose of Manchurian thorn depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Manchurian thorn. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- Brekhman II, Dardymov IV. New substances of plant origin which increase nonspecific resistance. Annu Rev Pharmacol 1969;9:419-30.
- Abidov MT, del Rio MJ, Ramazanov TZ, et al. Effects of Aralia mandshurica and Engelhardtia chrysolepis extracts on some parameters of lipid metabolism in women with nondiabetic obesity. Bull Exp Biol Med 2006;141(3):343-6.
- Burgos R, Hancke J, Caceres DD, et al. Hepatotoxic effect of Aralia mandshurica dried root extract in pigs. Phytotherapy Res 1997;11(1):59-61.
- Burgos R, Hancke J, Wikman G, et al. Toxicological assessment of Aralia mandshurica (Araliaceae) root extract after subchronic administration in rats. A biochemical and histological study. Phytotherapy Res 1994;8(1):1-9.
- Dong WC. [Determination of total aralosides in Aralia mandshurica grown in Jilin and Liaoning Provinces]. ZhongYao TongBao 1986;11(7):44-6.
- Iskenderov GB. [The metabolism of araloside A]. Farmakol Toksikol 1991;54(6):33-5.
- Mal'chukovskii LB, Takhtobaeva GM, et al. [Determination of the sum of aralosides A, B, C in the roots of Aralia mandshurica]. Farmatsiia 1972;21(6):45-7.
- Lutomski J, Nham NT. Studies on the saponin fraction from the root of Aralia mandshurica Rupr et Maxim Part I Chromatographic investigations. Herba Polonica 1977;23(1):5-11.
- Lutomski J, Gorecki P, Halasa J. [Immunologische Eigenschaften der Saponosidfraktion aus Aralia mandshurica]. Planta Med 1981;42(6):116-7.
- Martinez, B. and Staba, E. J. The physiological effects of Aralia, Panax and Eleutherococcus on exercised rats. Jpn J Pharmacol 1984;35(2):79-85.
- Wang M, Xu X, Xu H, et al. Effect of the total saponins of Aralia elata (Miq) Seem on cardiac contractile function and intracellular calcium cycling regulation. J Ethnopharmacol 2014;155(1):240-247.
- Shikov AN, Pozharitskaya ON, Makarov VG, et al. Medicinal plants of the Russian Pharmacopoeia; their history and applications. J Ethnopharmacol 2014;154(3):481-536.