Laxogenin
OTHER NAME(S): (2AR,2'R,4S,5'R,6aR,6bS,8aS,8bR,9S,11aS,12aS,12bS)-2a,4-Dihydroxy-5',6a,8a,9- Tetramethylicosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-2(11aH)-One, 25R,5Alpha-Spirostan-3Beta,5-Diol-6-One, 25-R-Spirostan-5A-Diol-6-One-3-One, (25R)-3 Beta-Hydroxy-5 Alpha-Spirostan-6-One, (25R)-3Beta,5Alpha-Dihydroxyspirostan-6-One, 5a-Hydroxy Laxogenin, 5-Alpha-Hydroxy Laxogenin, 25R Spirostan-5a-Diol-6-One-3-One Decanoate, 25R Spirostan-5a-Diol-6-One-3-One Undecanoate, Laxogenine, Laxosterone, Spirostan-6-One, 3,5-Dihydroxy-, (3beta,5alpha,25R)-, Spirostan-6-One, 3,5-Dihydroxy-, (3b,5a,25R)-, 16- hydroxy-5',7,9, 13-tetramethylspiro[5-oxapentacycloicosane-6,2'-oxane]-19-one, Laxogenina, Laxogénine
Overview
Laxogenin is a chemical found in plants. It stimulates plant growth. Laxogenin and a similar chemical, called 5-alpha-hydroxy laxogenin, are sold as medicine. However, there is no evidence to support their use.
Laxogenin and 5-alpha-hydroxy laxogenin are taken by mouth to build muscle and increase strength.
Laxogenin is a natural chemical found in plants. It helps the plant to grow. Some people think that it might promote muscle growth in humans. However, there is no evidence to support this.
Laxogenin is a natural chemical found in plants. It helps the plant to grow. Some people think that it might promote muscle growth in humans. However, there is no evidence to support this.
Uses
Insufficient Evidence for
- Muscle growth.
- Muscle strength.
More evidence is needed to rate laxogenin for these uses.
Side Effects
When taken by mouth: Laxogenin is POSSIBLY UNSAFE when taken by mouth as a supplement. Products claiming to contain laxogenin, or a related compound called 5-alpha-hydroxy laxogenin, usually contain other ingredients that might be unsafe. Some of these other ingredients are banned from use during sports competitions.
Precautions
When taken by mouth: Laxogenin is POSSIBLY UNSAFE when taken by mouth as a supplement. Products claiming to contain laxogenin, or a related compound called 5-alpha-hydroxy laxogenin, usually contain other ingredients that might be unsafe. Some of these other ingredients are banned from use during sports competitions.
Pregnancy and breast-feeding: There isn't enough reliable information to know if laxogenin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
We currently have no information for Laxogenin overview.
Dosing
The appropriate dose of laxogenin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for laxogenin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- Avula B, Chittiboyina AG, Bae JY, et al. The power of hyphenated chromatography-Time of flight mass spectrometry for unequivocal identification of spirostanes in bodybuilding dietary supplements. J Pharm Biomed Anal. 2019;167:74-82.
- Baba M, Ohmura M, Kishi N, et al. Saponins isolated from Allium chinense G. Don and antitumor-promoting activities of isoliquiritigenin and laxogenin from the same drug. Biol Pharm Bull. 2000;23(5):660-2.
- Kuroda M, Mimaki Y, Kameyama A, Sashida Y, Nikaido T. Steroidal saponins from Allium chinense and their inhibitory activities on cyclic AMP phosphodiesterase and Na+/K+ ATPase. Phytochemistry. 1995;40(4):1071-6.
- Esposito D, Komarnytsky S, Shapses S, Raskin I. Anabolic effect of plant brassinosteroid. FASEB J. 2011;25(10):3708-19.