Lactiplantibacillus Pentosus
OTHER NAME(S): L. pentosus, Lactobacillus pentosus, Lactiplantibacillus pentosus
Overview
Lactiplantibacillus pentosus (L. pentosus) is a type of probiotic ("good" bacteria) found naturally in the human body. It's also found in fermented foods.
"Good" bacteria such as L. pentosus might help the body break down food, absorb nutrients, and fight off "bad" organisms that might cause diseases. These bacteria are sometimes added to fermented foods like yogurt and also found in dietary supplements.
People use L. pentosus for eczema, common cold, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse L. pentosus with other probiotics, or with fermented food products such as fermented milk, kefir, or yogurt. These are not the same. Also note that L. pentosus used to be classified under the Lactobacillus genus. But Lactobacillus was split up into 25 different genera in April 2020. Some product labels might still list this species as Lactobacillus pentosus rather than its new name, Lactiplantibacillus pentosus.
Uses
We currently have no information for Lactiplantibacillus pentosus overview.
Side Effects
When taken by mouth: Live or heat-killed L. pentosus is possibly safe for most people. Heat-killed L. pentosus have been used safely in doses of up to 20 billion colony-forming units (CFUs) daily for up to 20 weeks. It seems to be well-tolerated.
Precautions
When taken by mouth: Live or heat-killed L. pentosus is possibly safe for most people. Heat-killed L. pentosus have been used safely in doses of up to 20 billion colony-forming units (CFUs) daily for up to 20 weeks. It seems to be well-tolerated.
Pregnancy and breast-feeding: There isn't enough reliable information to know if L. pentosus is safe to use when pregnant or breast-feeding. But there are no reasons to expect safety concerns when used appropriately.
Children: There isn't enough reliable information to know if L. pentosus is safe for children, including very small premature infants.
Weakened immune system: Probiotics have caused blood infections in a small number of people with weakened immune systems. If you have a weakened immune system, talk with your healthcare provider before taking probiotics, including L. pentosus.
Damaged heart valves: Probiotic preparations can cause an infection in the inner lining of the heart chambers and heart valve. This is extremely rare, but people with damaged heart valves should stop taking probiotics, including L. pentosus, before dental procedures or surgical procedures.
Interactions
Minor Interaction
Be watchful with this combination
- Antibiotic drugs interacts with Lactiplantibacillus pentosusL. pentosus is a type of friendly bacteria. Antibiotics are used to reduce harmful bacteria in the body. Taking antibiotics along with L. pentosus can reduce the effects of L. pentosus. To avoid this interaction, take L. pentosus products at least 2 hours before or after antibiotics.
Dosing
There isn't enough reliable information to know what an appropriate dose of L. pentosus might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Meydani SN, Ha WK. Immunologic effects of yogurt. Am J Clin Nutr 2000;71:861-72.
- Schultz M, Sartor RB. Probiotics and inflammatory bowel diseases. Am J Gastroenterol 2000;95:S19-21.
- de Roos NM, Katan MB. Effects of probiotic bacteria on diarrhea, lipid metabolism, and carcinogenesis: a review of papers published between 1988 and 1998. Am J Clin Nutr 2000;71:405-11.
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6.
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7.
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7.
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
- Isolauri E, Sutas Y, Kankaanpaa P, et al. Probiotics: effects on immunity. Am J Clin Nutr 2001;73:444S-450S.
- Franko B, Vaillant M, Recule C, Vautrin E, Brion JP, Pavese P. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect 2013;43(4):171-3.
- Roberfroid MB. Prebiotics and probiotics: are they functional foods? Am J Clin Nutr. 2000;71(6 Suppl):1682S-7S; discussion 1688S-90S.
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol 2016;224:157-61.
- Aaron JG, Sobieszczyk ME, Weiner SD, Whittier S, Lowy FD. Lactobacillus rhamnosus endocarditis after upper endoscopy. Open Forum Infect Dis 2017;4(2):ofx085.
- Zheng J, Wittouch S, Salvetti E, et al. A Taxonomic Note on the Genus Lactobacillus: Description of 23 Novel Genera, Emended Description of the Genus Lactobacillus Beijerinck 1901, and Union of Lactobacillaceae and Leuconostocaceae. Int J Syst Evol Microbiol. 2020 Apr 15. doi:10.1099/ijsem.0.004107.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178.
- Ahn SH, Yoon W, Lee SY, et al. Effects of Lactobacillus pentosus in children with allergen-sensitized atopic dermatitis. J Korean Med Sci 2020;35(18):e128.
- Thuy TTD, Kuo PY, Lin SM, Kao CY. Anti-helicobacter pylori activity of potential probiotic Lactiplantibacillus pentosus SLC13. BMC Microbiol 2022;22(1):277.
- Zeng Y, Zhang H, Tsao R, Mine Y. Lactobacillus pentosus S-PT84 prevents low-grade chronic inflammation-associated metabolic disorders in a lipopolysaccharide and high-fat diet C57/BL6J mouse model. J Agric Food Chem 2020;68(15):4374-4386.
- Zheng PX, Fang HY, Yang HB, Tien NY, Wang MC, Wu JJ. Lactobacillus pentosus strain LPS16 produces lactic acid, inhibiting multidrug-resistant Helicobacter pylori. J Microbiol Immunol Infect 2016;49(2):168-74.
- Shinkai S, Toba M, Saito T, et al. Immunoprotective effects of oral intake of heat-killed Lactobacillus pentosus strain b240 in elderly adults: a randomised, double-blind, placebo-controlled trial. Br J Nutr 2013;109(10):1856-65.
- Shimosato T, Tomida K, Otani H. Effect of Lactobacillus pentosus ONRIC b0240 on intestinal IgA production in mice fed differing levels of protein. J Agric Food Chem 2011;59(6):2646-51.
- Kotani Y, Shinkai S, Okamatsu H, et al. Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial. Immun Ageing. 2010;7:11.
- Poindexter B; Committee on fetus and newborn. Use of Probiotics in Preterm Infants. Pediatrics. 2021;147(6):e2021051485.
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259.
- Dani C, Coviello C C, Corsini I I, Arena F, Antonelli A, Rossolini GM. Lactobacillus Sepsis and Probiotic Therapy in Newborns: Two New Cases and Literature Review. AJP Rep. 2016;6(1):e25-9.
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7.
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.