Combretum Micranthum
OTHER NAME(S): Antidote à l'Opium, Antidote d'Opium, Antídoto de Opio, Combretum, Geza, Jungle Weed, Kinkeliba, Long-Life Herbal Tea, Opium Antidote, Plant to Heal, Combretum micranthum, Kinkéliba
Overview
Combretum micranthum is a type of shrub that is used as a beverage or as medicine in parts of Western Africa.
Combretum micranthum might stimulate bile flow, which is important in digestion. It might also have anti-inflammatory effects.
People use Combretum micranthum for high blood pressure, stomach upset, and many other conditions, but there is no scientific evidence to support these uses.
Uses
We currently have no information for Combretum micranthum overview.
Side Effects
When taken by mouth: Combretum micranthum is possibly safe when used for up to 6 months. Side effects might include stomach pain.
Precautions
When taken by mouth: Combretum micranthum is possibly safe when used for up to 6 months. Side effects might include stomach pain.
Pregnancy and breast-feeding: There isn't enough reliable information to know if Combretum micranthum is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications for diabetes (Antidiabetes drugs) interacts with Combretum micranthumCombretum micranthum leaf might lower blood sugar levels. Taking Combretum micranthum along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
- Medications for high blood pressure (Antihypertensive drugs) interacts with Combretum micranthumCombretum micranthum leaf might lower blood pressure. Taking Combretum micranthum along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.
- Water pills (Diuretic drugs) interacts with Combretum micranthumCombretum micranthum leaf can decrease potassium levels. "Water pills" can also decrease potassium levels. Taking Combretum micranthum along with "water pills" might make potassium levels drop too low.
Dosing
Combretum micranthum has most often been used by adults in doses of 200 mg by mouth twice daily for 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
References
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Ferrea G, Canessa A, Sampietro F, et al. In vitro activity of a Combretum micranthum extract against herpes simplex virus types 1 and 2. Antiviral Res 1993;21:317-25.
- Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020.
- Kpemissi M, Potârniche AV, Lawson-Evi P, et al. Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and in-silico experiments. J Ethnopharmacol 2020;261:113133.
- Kpemissi M, Eklu-Gadegbeku K, Veerapur VP, et al. Antioxidant and nephroprotection activities of Combretum micranthum: A phytochemical, in-vitro and ex-vivo studies. Heliyon 2019;5(3):e01365.
- Chika A, Bello SO. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats. J Ethnopharmacol 2010;129(1):34-7.
- Olajide OA, Makinde JM, Okpako DT. Evaluation of the anti-inflammatory property of the extract of Combretum micranthum G. Don (Combretaceae). Inflammopharmacology 2003;11(3):293-8.
- Seck SM, Doupa D, Dia DG, et al. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. J Hum Hypertens 2017;32(1):75-81.
- Ndiaye NF, Idohou-Dossou N, Bürkli S, et al. Polyphenol-rich tea decreases iron absorption from fortified wheat bread in Senegalese mother-child pairs and bioavailability of ferrous fumarate is sharply lower in children. Eur J Clin Nutr 2020;74(8):1221-1228.