Carbon 60 (C60)
OTHER NAME(S): Carbon Cage, Buckminsterfullerene, Buckyball, Fullerine C60, Carbon 60, Carbono 60 (C60), Carbone 60 (C60)
Overview
Carbon 60 is a molecule made up of 60 carbon atoms. The atoms form a molecule shaped like a soccer ball. There's interest in using it in supplements.
Carbon 60 was first used in nanotechnology and electronics. Carbon 60 is also an antioxidant with potential anti-aging effects. Antioxidants may help protect cells from free radicals.
People use carbon 60 for acne, aging skin, and other conditions, but there is no good scientific evidence to support any use. There is also no good evidence to support using carbon 60 for COVID-19.
Uses
We currently have no information for Carbon 60 (C60) overview.
Side Effects
When taken by mouth: There isn't enough reliable information to know if carbon 60 is safe or what the side effects might be.
When applied to the skin: Carbon 60 is possibly safe when used for up to 8 weeks.
Precautions
When taken by mouth: There isn't enough reliable information to know if carbon 60 is safe or what the side effects might be.
When applied to the skin: Carbon 60 is possibly safe when used for up to 8 weeks.
Pregnancy and breast-feeding: There isn't enough reliable information to know if carbon 60 is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
We currently have no information for Carbon 60 (C60) overview.
Dosing
A specific carbon 60 gel product (LipoFullerene, Vitamin C60 BioResearch Corporation) has most often been applied to the skin twice daily in adults. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
References
- Inui S, Aoshima H, Nishiyama A, Itami S. Improvement of acne vulgaris by topical fullerene application: unique impact on skin care. Nanomedicine. 2011;7(2):238-41.
- Kato S, Taira H, Aoshima H, Saitoh Y, Miwa N. Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.J Nanosci Nanotechnol. 2010 Oct;10(10):6769-74. Clinical Trial.
- Kolosnjaj J, Szwarc H, Moussa F. Toxicity studies of fullerenes and derivatives Adv Exp Med Biol. 2007;620:168-80.
- Grebinyk A, Grebinyk S, Prylutska S, et al. C60 fullerene accumulation in human leukemic cells and perspectives of LED-mediated photodynamic therapy. Free Radic Biol Med. 2018;124:319-327.
- Song M, Liu S, Yin J, Wang H. Interaction of human serum album and C60 aggregates in solution. Int J Mol Sci. 2011;12(8):4964-74.
- Song M, Yuan S, Yin J, et al. Size-dependent toxicity of nano-C60 aggregates: more sensitive indication by apoptosis-related Bax translocation in cultured human cells. Environ Sci Technol. 2012;46(6):3457-64.
- Torres VM, Srdjenovic B, Jacevic V, Simic VD, Djordjevic A, Simplício AL. Fullerenol C60(OH)24 prevents doxorubicin-induced acute cardiotoxicity in rats. Pharmacol Rep. 2010;62(4):707-18.
- Yudoh K, Karasawa R, Masuko K, Kato T. Water-soluble fullerene (C60) inhibits the development of arthritis in the rat model of arthritis. Int J Nanomedicine. 2009;4:217-25.
- Zhu X, Sollogoub M, Zhang Y. Biological applications of hydrophilic C60 derivatives (hC60s)- a structural perspective. Eur J Med Chem. 2016;115:438-52.
- Shytikov D, Shytikova I, Rohila D, Kulaga A, Dubiley T, Pishel I. Effect of long-term treatment with C60 fullerenes on the lifespan and health status of CBA/Ca mice. Rejuvenation Res. 2021;24(5):345-53.
- Durasevic S, Nikolic G, Todorovic A, et al. Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats. Food Chem Toxicol. 2020 Jun;140:111302.
- Demir E. Therapeutic effect of curcumin and C60 fullerene against hyperglycemia-mediated tissue damage in diabetic rat lungs. J Bioenerg Biomembr. 2021;53(1):25-38.