Bryonia
OTHER NAME(S): Bryoniae Radix, Bryone Blanche, Bryone Dioïque, Couleuvrée, Devil's Turnip, English Mandrake, Herbe de Feu, Ladies' Seal, Mandragore Grimpante, Navet du Diable, Rave de Serpent, Tamus, Tetterberry, Vigne Blanche, Vigne du Diable, White Bryony, Wild Hops, Wild Nep, Wild Vine, Wood Vine, Bryonia cretica, Bryonia alba, Bryonia Dioca, Brionia, Bryone
Overview
Bryonia is a plant. People use the root for medicine. The berries of the plant are poisonous.
Bryonia root is used as a laxative, to induce vomiting, for liver disease, infection, and many other conditions, but there is no good scientific evidence to support these uses. Using bryonia root is also likely unsafe.
Bryonia root contains chemicals that might reduce inflammation. Bryonia berries contain a toxic chemical that can be fatal.
Bryonia root contains chemicals that might reduce inflammation. Bryonia berries contain a toxic chemical that can be fatal.
Uses
Insufficient Evidence for
- Stomach or intestinal diseases.
- Lung diseases.
- Arthritis.
- Liver disease.
- Metabolic disorders.
- Fluid retention.
- Preventing infections.
- Causing vomiting.
- Other conditions.
More evidence is needed to rate the effectiveness of bryonia for these uses.
Side Effects
When taken by mouth: Bryonia is LIKELY UNSAFE for anyone to use. Even in low doses, the root can cause many side effects, including dizziness, vomiting, convulsions, bloody diarrhea, nervous excitement, and kidney damage. Larger doses of the root may cause fatal poisoning. Eating the berries of the bryonia plant can cause death. As few as 40 berries can be fatal in an adult.
Precautions
When taken by mouth: Bryonia is LIKELY UNSAFE for anyone to use. Even in low doses, the root can cause many side effects, including dizziness, vomiting, convulsions, bloody diarrhea, nervous excitement, and kidney damage. Larger doses of the root may cause fatal poisoning. Eating the berries of the bryonia plant can cause death. As few as 40 berries can be fatal in an adult.
It's LIKELY UNSAFE for anyone to take bryonia by mouth. But bryonia is especially dangerous for people with the following conditions:
Pregnancy: Bryonia is UNSAFE for pregnant women when taken by mouth. It can cause a miscarriage.
Children: Bryonia is LIKELY UNSAFE for children when taken by mouth. The root can cause serious side effects. Eating as few as 15 berries can cause death.
Breast-feeding: Bryonia is LIKELY UNSAFE for breast-feeding women when taken by mouth. It can cause serious health consequences.
Stomach and intestinal (gastrointestinal, GI) disorders: There are many reasons not to use bryonia. It can cause serious side effects and death. Additionally, it can irritate the stomach and intestines and can make GI problems worse.
Interactions
We currently have no information for Bryonia overview.
Dosing
The appropriate dose of bryonia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for bryonia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
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- Panosian, A. G. [Effect of Bryonia cucurbitacins on the biosynthesis of eicosanoids in human leukocytes]. Bioorg.Khim. 1985;11(2):264-269.
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- Vartanian, G. S., Parsadanian, G. K., and Karagezian, K. G. [Effect of trihydroxyoctadecadiene acids from Bryonia alba L. on the activity of glycogen metabolism enzymes in alloxan diabetes]. Biull.Eksp.Biol.Med. 1984;97(3):295-297.
- Panossian, A. G., Avetissian, G. M., Mnatsakanian, V. A., Batrakov, S. G., Vartanian, S. A., Gabrielian, E. S., and Amroyan, E. A. Unsaturated polyhydroxy acids having prostaglandin-like activity from Bryonia alba II. Major components. Planta Med. 1983;47(1):17-25.
- Vartanian, G. S. and Karagezian, K. G. [Normalizing effect of Bryonia alba L. on blood phospholipids in alloxan diabetes]. Vopr.Med.Khim. 1981;27(2):179-181.
- Karagezian, K. G., Vartanian, G. S., and Panosian, A. G. [Effect of an extract from the roots of bryony (Bryonia alba) on lipid peroxidation in the liver of rats with alloxan diabetes]. Biull.Eksp.Biol.Med. 1981;92(8):35-37.
- Siegall, C. B., Gawlak, S. L., Chace, D., Wolff, E. A., Mixan, B., and Marquardt, H. Characterization of ribosome-inactivating proteins isolated from Bryonia dioica and their utility as carcinoma-reactive immunoconjugates. Bioconjug.Chem. 1994;5(5):423-429.
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- Gawlak, S. L., Neubauer, M., Klei, H. E., Chang, C. Y., Einspahr, H. M., and Siegall, C. B. Molecular, biological, and preliminary structural analysis of recombinant bryodin 1, a ribosome-inactivating protein from the plant Bryonia dioica. Biochemistry 3-18-1997;36(11):3095-3103.
- Francisco, J. A., Gawlak, S. L., Miller, M., Bathe, J., Russell, D., Chace, D., Mixan, B., Zhao, L., Fell, H. P., and Siegall, C. B. Expression and characterization of bryodin 1 and a bryodin 1-based single-chain immunotoxin from tobacco cell culture. Bioconjug.Chem. 1997;8(5):708-713.
- Karageuzyan, K. G., Vartanyan, G. S., Agadjanov, M. I., Panossian, A. G., and Hoult, J. R. Restoration of the disordered glucose-fatty acid cycle in alloxan-diabetic rats by trihydroxyoctadecadienoic acids from Bryonia alba, a native Armenian medicinal plant. Planta Med. 1998;64(5):417-422.