Bay Leaf

OTHER NAME(S): Bay, Bay Laurel, Bay Tree, Daphne, Grecian Laurel, Laurel, Laurel Común, Laurier d'Apollon, Laurier Noble, Laurier-Sauce, Laurier Vrai, Mediterranean Bay, Noble Laurel, Roman Laurel, Sweet Bay, Sweet Laurel, True Bay, True Laurel, Laurus nobilis, Hoja de Laurel, Feuille de laurier

Overview

Bay leaf is an herb that is commonly used in cooking. It comes from the bay tree (Laurus nobilis), which is commonly found in the Mediterranean region.

Bay leaf is also used in folk medicine. Chemicals in bay leaf might affect blood sugar and cholesterol levels.

People use bay leaf for diabetes, common cold, high cholesterol, asthma, and many other conditions, but there is no good scientific evidence to support these uses.

References
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  3. Tyler VE. Herbs of Choice. Binghamton, NY: Pharmaceutical Products Press, 1994.
  4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  7. Buto SK, Tsang TK, Sielaff GW, et al. Bay leaf impaction in the esophagus and hypopharynx. Ann Intern Med 1990;113:82-3.
  8. Johns AN. Beware of the bay leaf. Br Med J 1980;281:1682.
  9. Belitsos NJ. Bay leaf impaction. Ann Intern Med 1990;113:483-4.
  10. Bell CD, Mustar RA. Bay leaf perforation of Meckel's diverticulum. JCC 1997;40:146.
  11. Palin WE, Richardson JD. Complications from bay leaf ingestions. JAMA 1983;289:729-30.
  12. Brokaw SA. Complications of bay leaf ingestion [letter]. JAMA 1983;250:729.
  13. Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9.
  14. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  15. Broadhurst CL, Polansky MM, Anderson RA. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 2000;48:849-52..
  16. Adisen E, Onder M. Allergic contact dermatitis from Laurus nobilis oil induced by massage. Contact Dermatitis 2007;56:360-1.
  17. Tsang, T. K., Flais, M. J., and Hsin, G. Duodenal obstruction secondary to bay leaf impaction. Ann Intern Med 4-20-1999;130(8):701-702.
  18. Ozden, M. G., Oztas, P., Oztas, M. O., and Onder, M. Allergic contact dermatitis from Laurus nobilis (laurel) oil. Contact Dermatitis 2001;45(3):178.
  19. Caredda, A., Marongiu, B., Porcedda, S., and Soro, C. Supercritical carbon dioxide extraction and characterization of Laurus nobilis essential oil. J Agric.Food Chem. 3-13-2002;50(6):1492-1496.
  20. Sayyah, M., Valizadeh, J., and Kamalinejad, M. Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizures. Phytomedicine. 2002;9(3):212-216.
  21. Hibasami, H., Yamada, Y., Moteki, H., Katsuzaki, H., Imai, K., Yoshioka, K., and Komiya, T. Sesquiterpenes (costunolide and zaluzanin D) isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells. Int J Mol.Med 2003;12(2):147-151.
  22. Gurman, E. G., Bagirova, E. A., and Storchilo, O. V. [The effect of food and drug herbal extracts on the hydrolysis and transport of sugars in the rat small intestine under different experimental conditions]. Fiziol.Zh.SSSR Im I.M.Sechenova 1992;78(8):109-116.
  23. Komiya, T., Yamada, Y., Moteki, H., Katsuzaki, H., Imai, K., and Hibasami, H. Hot water soluble sesquiterpenes [anhydroperoxy-costunolide and 3-oxoeudesma-1,4(15),11(13)triene-12,6alpha-olide] isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia cells. Oncol.Rep. 2004;11(1):85-88.
  24. Simic, A., Sokovic, M. D., Ristic, M., Grujic-Jovanovic, S., Vukojevic, J., and Marin, P. D. The chemical composition of some Lauraceae essential oils and their antifungal activities. Phytother Res 2004;18(9):713-717.
  25. Lingenfelser, T., Adams, G., Solomons, D., and Marks, I. N. Bay leaf perforation of the small bowel in a patient with chronic calcific pancreatitis. J Clin.Gastroenterol. 1992;14(2):174-176.
  26. De Marino, S., Borbone, N., Zollo, F., Ianaro, A., Di Meglio, P., and Iorizzi, M. Megastigmane and phenolic components from Laurus nobilis L. leaves and their inhibitory effects on nitric oxide production. J Agric.Food Chem. 12-15-2004;52(25):7525-7531.
  27. Dall'Acqua, S., Viola, G., Giorgetti, M., Loi, M. C., and Innocenti, G. Two new sesquiterpene lactones from the leaves of Laurus nobilis. Chem.Pharm.Bull (Tokyo) 2006;54(8):1187-1189.
  28. Conforti, F., Statti, G., Uzunov, D., and Menichini, F. Comparative chemical composition and antioxidant activities of wild and cultivated Laurus nobilis L. leaves and Foeniculum vulgare subsp. piperitum (Ucria) coutinho seeds. Biol.Pharm.Bull 2006;29(10):2056-2064.
  29. Kaileh, M., Berghe, W. V., Boone, E., Essawi, T., and Haegeman, G. Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity. J Ethnopharmacol. 9-25-2007;113(3):510-516.
  30. Loizzo, M. R., Tundis, R., Menichini, F., Saab, A. M., Statti, G. A., and Menichini, F. Cytotoxic activity of essential oils from labiatae and lauraceae families against in vitro human tumor models. Anticancer Res 2007;27(5A):3293-3299.
  31. Yalcin, H., Anik, M., Sanda, M. A., and Cakir, A. Gas chromatography/mass spectrometry analysis of Laurus nobilis essential oil composition of northern Cyprus. J Med Food 2007;10(4):715-719.
  32. Loizzo, M. R., Saab, A. M., Tundis, R., Statti, G. A., Menichini, F., Lampronti, I., Gambari, R., Cinatl, J., and Doerr, H. W. Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chem.Biodivers. 2008;5(3):461-470.
  33. Tepkeeva, I. I., Moiseeva, E. V., Chaadaeva, A. V., Zhavoronkova, E. V., Kessler, Y. V., Semushina, S. G., and Demushkin, V. P. Evaluation of antitumor activity of peptide extracts from medicinal plants on the model of transplanted breast cancer in CBRB-Rb(8.17)1Iem mice. Bull Exp.Biol.Med 2008;145(4):464-466.
  34. Khan, A., Zaman, G., and Anderson, R. A. Bay leaves improve glucose and lipid profile of people with type 2 diabetes. J Clin Biochem.Nutr. 2009;44(1):52-56.
  35. Verdian-rizi, M. and Hadjiakhoondi, A. Essential oil composition of Laurus nobilis L. of different growth stages growing in Iran. Z.Naturforsch.C 2008;63(11-12):785-788.
  36. Dall'Acqua, S., Cervellati, R., Speroni, E., Costa, S., Guerra, M. C., Stella, L., Greco, E., and Innocenti, G. Phytochemical composition and antioxidant activity of Laurus nobilis L. leaf infusion. J Med Food 2009;12(4):869-876.
  37. Cheminat, A., Stampf, J. L., and Benezra, C. Allergic contact dermatitis to laurel (Laurus nobilis L.): isolation and identification of haptens. Arch Dermatol Res 1984;276(3):178-181.
  38. Awerbuck, D. C., Briant, T. D., and Wax, M. K. Bay leaf: an uncommon foreign body of the hypopharynx. Otolaryngol Head Neck Surg 1994;110(3):338-340.
  39. Bell, C. D. and Mustard, R. A. Bay leaf perforation of Meckel's diverticulum. Can.J Surg 1997;40(2):146-147.
  40. Skok, P. Dried bay leaf: an unusual cause of upper gastrointestinal tract hemorrhage. Endoscopy 1998;30(3):S40-S41.
  41. Medeiros-Fonseca B, Mestre VF, Colaço B, et al. Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. Food Funct. 2018;9(8):4419-4428.
  42. Chbili C, Maoua M, Selmi M, et al. Evaluation of daily Laurus nobilis tea consumption on lipid profile biomarkers in healthy volunteers. J Am Coll Nutr. Nov-Dec 2020;39(8):733-738.
  43. Vassileva S, Darlenski R. Bay leaf phytodermatitis. Contact Dermatitis. 2020 Nov 15.
  44. Odeh D, Orsolic N, Berendika M, et al. Antioxidant and Anti-Atherogenic Activities of Essential Oils from Myrtus communis L. and Laurus nobilis L. in Rat. Nutrients 2022;14(7):1465.
  45. Bouadid I, Amssayef A, Eddouks M. Study of the Antihypertensive Effect of Laurus nobilis in Rats. Cardiovasc Hematol Agents Med Chem 2022.