Ascorbigen
OTHER NAME(S): AGN, Ascrobigène, Indole, Ascorbigen, Ascorbigène
Overview
Ascorbigen is a chemical found in broccoli, cauliflower, cabbage, kale, and related vegetables. It is sometimes used to make medicine.
People use ascorbigen for fibromyalgia, preventing cancer, and many other purposes, but there is no good scientific evidence to support any use.
Do not confuse ascorbigen with indole-3-carbinol, a similar chemical found in the same vegetables.
Uses
We currently have no information for Ascorbigen overview.
Side Effects
When taken by mouth: Ascorbigen is found in many vegetables, including broccoli, cauliflower, kale, and others. But there isn't enough reliable information to know if ascorbigen is safe to use in larger amounts as medicine.
Precautions
When taken by mouth: Ascorbigen is found in many vegetables, including broccoli, cauliflower, kale, and others. But there isn't enough reliable information to know if ascorbigen is safe to use in larger amounts as medicine.
Pregnancy and breast-feeding: There isn't enough reliable information to know if ascorbigen is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
We currently have no information for Ascorbigen overview.
Dosing
There isn't enough reliable information to know what an appropriate dose of ascorbigen might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Kravchenko LV, Avren'eva LI, Guseva GV, et al. Effect of nutritional indoles on activity of xenobiotic metabolism enzymes and T-2 toxicity in rats. Bull Exp Biol Med 2001;131:544-7.
- Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 2001;61:6120-30.
- Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.
- Buskov S, Hansen LB, Olsen CE, et al. Determination of ascorbigens in autolysates of various Brassica species using supercritical fluid chromatography. J Agric Food Chem 2000;48:2693-701.
- Sepkovic DW, Bradlow HL, Michnovicz J, et al. Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or beta-naphthaflavone: a comparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods. Steroids 1994;59:318-23.