Blackberry
OTHER NAME(S): Bramble, Dewberry, Feuilles de Mûrier, Feuilles de Ronce, Goutberry, Mûre, Mûre Sauvage, Ronce du Canada, Ronce Commune, Ronce Laciniée, Rubi Fruticosi Folium, Rubi Fruticosi Radix, Thimbleberry, Rubus plicatus, Rubus fruticosus, Rubus affinis, Rubus canadensis, Rubus millspaughii, Rubus laciniatus, Black Berry, Zarzamora, Mûrier
Overview
Blackberry is a plant. The leaf, root, and fruit (berry) are used to make medicine.
Blackberry is used for diarrhea, fluid retention, diabetes, gout, pain and swelling (inflammation), throat irritation, and other conditions, but there is no good scientific evidence to support these uses.
Blackberry contains chemicals that might have antioxidant effects. It also contains chemicals that might protect against cancer.
Blackberry contains chemicals that might have antioxidant effects. It also contains chemicals that might protect against cancer.
Uses
Insufficient Evidence for
- Fluid retention.
- Diabetes.
- Diarrhea.
- Gout.
- Pain and swelling (inflammation).
- Cancer.
- Heart disease.
- Other conditions.
More evidence is needed to rate the effectiveness of blackberry for these uses.
Side Effects
When taken by mouth: Blackberry fruit is LIKELY SAFE in the amounts commonly found in food. There isn't enough reliable information to know if blackberry is safe in the larger amounts used as medicine or what the side effects might be.
Precautions
When taken by mouth: Blackberry fruit is LIKELY SAFE in the amounts commonly found in food. There isn't enough reliable information to know if blackberry is safe in the larger amounts used as medicine or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if blackberry is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.
Interactions
We currently have no information for Blackberry overview.
Dosing
The appropriate dose of blackberry for use as treatment depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for blackberry. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Ivanovska N, Philipov S. Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. Int J Immunopharmacol 1996;18:553-61.
- Wada L, Ou B. Antioxidant activity and phenolic content of Oregon caneberries. J Agric Food Chem 2002;50:3495-500..
- Wang SY, Jiao H. Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J Agric Food Chem 2000;48:5677-84..
- Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6..
- Siriwoharn T, Wrolstad RE, Finn CE, Pereira CB. Et al. Influence of cultivar, maturity, and sampling on blackberry (Rubus L. Hybrids) anthocyanins, polyphenolics, and antioxidant properties. J Agric Food Chem 2004;52:8021-30. .
- Feng R, Bowman LL, Lu Y, et al. Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway. Nutr Cancer 2004;50:80-9. .
- Serraino I, Dugo L, Dugo P, et al. Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure. Life Sci 2003;73:1097-114..
- Rossi A, Serraino I, Dugo P, et al. Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation. Free Radic Res 2003;37:891-900..
- Sauebin L, Rossi A, Serraino I, et al. Effect of anthocyanins contained in a blackberry extract on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat. Planta Med 2004;70:745-52. .
- Alonso R, Cadavid I, Calleja JM. A preliminary study of hypoglycemic activity of Rubus fruticosus. Planta Med 1980;Suppl:102-6..
- Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4.
- Blomhoff, R. [Antioxidants and oxidative stress]. Tidsskr.Nor Laegeforen. 6-17-2004;124(12):1643-1645.
- Netzel, M., Strass, G., Janssen, M., Bitsch, I., and Bitsch, R. Bioactive anthocyanins detected in human urine after ingestion of blackcurrant juice. J Environ.Pathol Toxicol Oncol 2001;20(2):89-95.
- Carmen Ramirez-Tortosa, M., Garcia-Alonso, J., Luisa Vidal-Guevara, M., Quiles, J. L., Jesus, Periago M., Linde, J., Dolores, Mesa M., Ros, G., Abellan, P., and Gil, A. Oxidative stress status in an institutionalised elderly group after the intake of a phenolic-rich dessert. Br J Nutr 2004;91(6):943-950.
- Halvorsen, B. L., Holte, K., Myhrstad, M. C., Barikmo, I., Hvattum, E., Remberg, S. F., Wold, A. B., Haffner, K., Baugerod, H., Andersen, L. F., Moskaug, O., Jacobs, D. R., Jr., and Blomhoff, R. A systematic screening of total antioxidants in dietary plants. J Nutr 2002;132(3):461-471.
- Pellegrini, N., Serafini, M., Colombi, B., Del Rio, D., Salvatore, S., Bianchi, M., and Brighenti, F. Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. J Nutr 2003;133(9):2812-2819.
- Spínola V, Pinto J, Llorent-Martínez EJ, Tomás H, Castilho PC. Evaluation of Rubus grandifolius L. (wild blackberries) activities targeting management of type-2 diabetes and obesity using in vitro models. Food Chem Toxicol. 2019 Jan;123:443-452.
- Solverson PM, Rumpler WV, Leger JL, et al. Blackberry Feeding Increases Fat Oxidation and Improves Insulin Sensitivity in Overweight and Obese Males. Nutrients. 2018 Aug 9;10(8). pii: E1048.
- Gowd V, Bao T, Wang L, et al. Antioxidant and antidiabetic activity of blackberry after gastrointestinal digestion and human gut microbiota fermentation. Food Chem. 2018 Dec 15;269:618-627.
- Fernández-Demeneghi R, Rodríguez-Landa JF, Guzmán-Gerónimo RI, et al. Effect of blackberry juice (Rubus fruticosus L.) on anxiety-like behaviour in Wistar rats. Int J Food Sci Nutr 2019;70(7):856-67.
- Mirazi N, Hosseini A. Attenuating properties of Rubus fruticosus L. on oxidative damage and inflammatory response following streptozotocin-induced diabetes in the male Wistar rats. J Diabetes Metab Disord 2020;19(2):1311-1316.
- Miller CS, Danaher RJ, Kirakodu S, Carlson CR, Mumper RJ. Effect of chewing gum containing Xylitol and blackberry powder on oral bacteria: A randomized controlled crossover trial. Arch Oral Biol. 2022 Nov;143:105523. doi: 10.1016/j.archoralbio.2022.105523.