Black Mulberry
OTHER NAME(S): Morera Negra, Mulberry, Purple Mulberry, Morus nigra, Mora Negra, Mûrier Noir
Overview
Black mulberry (Morus nigra) is a plant found worldwide. The ripe berry, twigs, and root bark are used to make medicine. The ripe berry is also eaten.
Black mulberry fruit contains pectin, which might act as a laxative. Chemicals in black mulberry fruit and black mulberry twigs might have blood sugar lowering effects.
People use black mulberry for constipation, symptoms of menopause, runny nose, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse black mulberry with white mulberry. These are not the same.
Uses
We currently have no information for Black Mulberry overview.
Side Effects
When taken by mouth: Black mulberry fruit and the molasses made from the fruit is possibly safe when eaten as a food. The fruit is commonly used in foods, but there isn't enough reliable information to know if it is safe to use as a medicine. Black mulberry leaf is possibly safe when taken as a medicine, short-term. Black mulberry leaf powder has been used safely for up to 60 days.
Precautions
When taken by mouth: Black mulberry fruit and the molasses made from the fruit is possibly safe when eaten as a food. The fruit is commonly used in foods, but there isn't enough reliable information to know if it is safe to use as a medicine. Black mulberry leaf is possibly safe when taken as a medicine, short-term. Black mulberry leaf powder has been used safely for up to 60 days.
Pregnancy and breast-feeding: There isn't enough reliable information to know if black mulberry is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Allergies: People who are allergic to fig might also be allergic to black mulberry.
Surgery: Black mulberry seems to lower blood sugar levels. It might interfere with blood sugar control during and after surgery. Stop using black mulberry at least 2 weeks before a scheduled surgery.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications for diabetes (Antidiabetes drugs) interacts with Black MulberryBlack mulberry leaf might lower blood sugar levels. Taking black mulberry leaf along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
- Midazolam (Versed) interacts with Black MulberryThe body breaks down midazolam to get rid of it. Black mulberry might slow the breakdown of midazolam. This might increase the effects and side effects of midazolam.
Dosing
There isn't enough reliable information to know what an appropriate dose of black mulberry might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- de Souza, M. M., Bittar, M., Cechinel-Filho, V., Yunes, R. A., Messana, I., Delle, Monache F., and Ferrari, F. Antinociceptive properties of morusin, a prenylflavonoid isolated from Morus nigra root bark. Z Naturforsch.[C.] 2000;55(3-4):256-260.
- Kim, H., Yoon, Y. J., Shon, J. H., Cha, I. J., Shin, J. G., and Liu, K. H. Inhibitory effects of fruit juices on CYP3A activity. Drug Metab Dispos. 2006;34(4):521-523.
- Muntean, D., Imre, S., Avrigeanu, V., and Csedo, C. Physico-chemical study of the isolated flavonoids from leaves and bark of Morus alba L. and Morus nigra L. species. Farmacia 2002;50:97-103.
- Caiaffa, M. F., Cataldo, V. M., Tursi, A., and Macchia, L. Fig and mulberry cross-allergy. Ann.Allergy Asthma Immunol. 2003;91(5):493-495.
- Demir Dogan M, Can G, Meral R. Effectiveness of black mulberry molasses in prevention of radiotherapy-induced oral mucositis: A randomized controlled study in head and neck cancer patients. J Altern Complement Med. 2017;23(12):971-979.
- Imran M, Khan H, Shah M, Khan R, Khan F. Chemical composition and antioxidant activity of certain Morus species. J Zhejiang Univ Sci B. 2010;11(12):973-80.
- Costa JPL, Brito HO, Galvão-Moreira LV, Brito LGO, Costa-Paiva L, Brito LMO. Randomized double-blind placebo-controlled trial of the effect of Morus nigra L. (black mulberry) leaf powder on symptoms and quality of life among climacteric women. Int J Gynaecol Obstet 2020;148(2):243-52.
- Xu LJ, Yu MH, Huang CY, et al. Isoprenylated flavonoids from Morus nigra and their PPAR ? agonistic activities. Fitoterapia 2018;127:109-14.
- Yazdankhah S, Hojjati M, Azizi MH. The antidiabetic potential of black mulberry extract-enriched pasta through inhibition of enzymes and glycemic index. Plant Foods Hum Nutr 2019;74(1):149-55.
- Momeni H, Salehi A, Absalan A, Akbari M. Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silico analysis. J Complement Integr Med 2021.
- Korkut S, Karadag S, Levent Çinar S. The effect of oral care with black mulberry syrup on oral mucositis in patients with COPD: a mixed study. Altern Ther Health Med 2021.
- Navarro-Triviño FJ, Jadczak P, Llamas-Molina JM, Ruiz-Villaverde R. Lichenoid contact dermatitis caused by Morus nigra L. Contact Dermatitis 2021;84(6):484-486.
- Karabey T, Karagözogli S, Aygün N, Sümer Z. The Effect of Oral Care With Black Mulberry Extract on Oral Mucositis, Dry Mouth, and Weight Gain in Patients With Cancer. Clin J Oncol Nurs 2022;26(6):636-642.