Yew
OTHER NAME(S): Arbre Sacré des Druides, Chinwood, Common Yew, English Yew, European Yew, Himalayan Yew, If à Baies, If Commun, If de l'Himalaya, If de l'Ouest, Ifreteau, Japanese Yew, Pacific Yew, Taleespatra, Talispatra, Western Yew, Taxus brevifolia, Taxus baccata, and other Taxus species.u003Cbru003EFamily: Taxaceae., Taxus bacatta, Tejo, If
Overview
Yew is an evergreen tree. People use the bark, branch tips, and needles to make medicine. Paclitaxel (Taxol), a prescription drug for the treatment of breast and ovarian cancer, originally came from the bark of the yew tree. But now paclitaxel is made in a lab.
Despite serious safety concerns, yew is used for promoting menstruation and causing abortion, treating certain parasite infections, and many other conditions, but there is no good scientific evidence to support any of these uses.
It is not known how yew might work as a medicine. The chemicals in yew are toxic, especially to cells in the heart. They cause the heart cells to work differently, making the heart beat faster and slower.
It is not known how yew might work as a medicine. The chemicals in yew are toxic, especially to cells in the heart. They cause the heart cells to work differently, making the heart beat faster and slower.
Uses
Insufficient Evidence for
- Menstrual disorders.
- Abortion.
- Tapeworms.
- Swollen tonsils.
- Epilepsy (seizures).
- Kidney problems.
- Liver problems.
- Cancer.
- Other conditions.
More evidence is needed to rate the effectiveness of yew for these uses.
Side Effects
When taken by mouth: Yew is LIKELY UNSAFE for people. All parts of the yew plant are considered poisonous. Yew can cause severe stomach problems. It can also cause the heart rate to slow down or speed up dangerously. Signs of poisoning might include nausea, dry mouth, vomiting, stomach pain, dizziness, weakness, nervousness, heart problems, and many others. Death has occurred after taking 50-100 grams of yew needles.
When applied to the skin: There isn't enough reliable information to know if yew is safe or what the side effects might be.
Precautions
When taken by mouth: Yew is LIKELY UNSAFE for people. All parts of the yew plant are considered poisonous. Yew can cause severe stomach problems. It can also cause the heart rate to slow down or speed up dangerously. Signs of poisoning might include nausea, dry mouth, vomiting, stomach pain, dizziness, weakness, nervousness, heart problems, and many others. Death has occurred after taking 50-100 grams of yew needles.
When applied to the skin: There isn't enough reliable information to know if yew is safe or what the side effects might be.
It is LIKELY UNSAFE for anyone to take yew, but some people have extra reasons not to use it:
Pregnancy and breast-feeding: It is UNSAFE for women who are pregnant or breast-feeding to take yew. Yew needles might cause an abortion. Also, taking the needles can poison the mother.
Children: It is UNSAFE for children to eat the berries or needles of yew. Swallowing one berry can be fatal in a child. Eating the berries or needles can also cause the heart to beat dangerously slow or fast.
Interactions
We currently have no information for Yew overview.
Dosing
The appropriate dose of yew depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for yew. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Robbers JE, Speedie MK, Tyler VE. Pharmacognosy and Pharmacobiotechnology. Baltimore, MD: Williams & Wilkins, 1996.
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Gossel TA, Bricker JD. Principles of Clinical Toxicology. New York, NY:Raven Press, 1994.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Sinn LE, Porterfield JF. Fatal taxine poisoning from yew leaf ingestion. J Forensic Sci 1991;36:599-601.
- Van IG, Visser R, Peltenburg H, et al. Sudden unexpected death due to Taxus poisoning. A report of five cases, with review of the literature. Forensic Sci Int 1992;56:81-7.
- Krenzelok EP, Jacobsen TD, Aronis J. Is the yew really poisonous to you? J Toxicol Clin Toxicol 1998;36:219-23.
- Maguchi, S. and Fukuda, S. Taxus cuspidata (Japanese yew) pollen nasal allergy. Auris Nasus Larynx 2001;28 Suppl:S43-S47.
- Willaert, W., Claessens, P., Vankelecom, B., and Vanderheyden, M. Intoxication with taxus baccata: cardiac arrhythmias following yew leaves ingestion. Pacing Clin.Electrophysiol. 2002;25(4 Pt 1):511-512.
- Cummins, R. O., Haulman, J., Quan, L., Graves, J. R., Peterson, D., and Horan, S. Near-fatal yew berry intoxication treated with external cardiac pacing and digoxin-specific FAB antibody fragments. Ann.Emerg.Med. 1990;19(1):38-43.
- Feldman, R., Chrobak, J., Liberek, Z., and Szajewski, J. [4 cases of poisoning with the extract of yew (Taxus baccata) needles]. Pol.Arch.Med.Wewn. 1988;79(1):26-29.
- Yersin, B., Frey, J. G., Schaller, M. D., Nicod, P., and Perret, C. Fatal cardiac arrhythmias and shock following yew leaves ingestion. Ann.Emerg.Med. 1987;16(12):1396-1397.
- Stebbing, J., Simmons, H. L., and Hepple, J. Deliberate self-harm using yew leaves (Taxus baccata). Br.J.Clin.Pract. 1995;49(2):101.
- von der, Werth J. and Murphy, J. J. Cardiovascular toxicity associated with yew leaf ingestion. Br.Heart J. 1994;72(1):92-93.
- Musshoff, F., Jacob, B., Fowinkel, C., and Daldrup, T. Suicidal yew leave ingestion--phloroglucindimethylether (3,5-dimethoxyphenol) as a marker for poisoning from Taxus baccata. Int.J.Legal Med. 1993;106(1):45-50.
- de Vos FYFL, van Laarhoven HMW. Taxus baccata allergy in a breast cancer patient. Neth J Med. 2012;70(5):249-0.
- Persico A, Bacis G, Uberti F, et al. Identification of taxine derivatives in biological fluids from a patient after attempted suicide by ingestion of yew (Taxus baccata) leaves. J Anal Toxicol. 2011;35(4):238-41.
- Pilija V, Djurendic-Brenesel M, Miletic S. Fatal poisoning by ingestion of Taxus Baccata leaves. Forensic Sci Int. 2018;290:e1-e4.
- Farag M, Badowski D, Koschny R, Skopp G, Brcic A, Szabo GB. Extracorporeal life support and digoxin-specific Fab fragments for successful management of Taxus baccata intoxication with low output and ventricular arrhythmia. Am J Emerg Med. 2017;35(12):1987.e3-1987.e7.
- Vardon Bounes F, Tardif E, Ruiz S, Gallart JC, Conil JM, Delmas C. Suicide attempt with self-made Taxus baccata leaf capsules: survival following the application of extracorporeal membrane oxygenation for ventricular arrythmia and refractory cardiogenic shock. Clin Toxicol (Phila). 2017;55(8):925-928.
- Baum C, Bohnen S, Sill B, et al. Prolonged resuscitation and cardiogenic shock after intoxication with European yew (Taxus baccata): Complete recovery after intermittent mechanical circulatory support. Int J Cardiol. 2015;181:176-8.
- 100041 Grobosch T, Schwarze B, Felgenhauer N, Riesselmann B, Roscher S, Binscheck T. Eight cases of fatal and non-fatal poisoning with Taxus baccata. Forensic Sci Int. 2013;227(1-3):118-26.
- Hermes-Laufer J, Meyer M, Rudiger A, et al. Extracorporeal life support as bridge to recovery in yew poisoning: case reports and literature review. ESC Heart Fail. 2021 Feb;8(1):705-709.
- G N, Chan M, Gue YX, Gorog DA. Fatal heart block from intentional yew tree (Taxus baccata) ingestion: a case report. Eur Heart J Case Rep. 2019 Dec 23;4(1):1-4.