Wasabi
OTHER NAME(S): Berkstockrose, Gochunaengi, Japanese Horseradish, Japanese Wasabi, Japanischer Meerrettich, Korean Wasabi, Eutrema japonicum, Wasabia japonica, Cochlearia wasabi, Eutrema wasabi, Wasabia koreana, Wasabia japonica var. koreana
Overview
Wasabi is a plant native to Japan. It's mainly grown for its roots, which are ground to make a spice. It's sometimes called Japanese horseradish.
Wasabi contains chemicals that may have anticancer effects and anti-inflammatory effects and may also slow blood clotting.
People take wasabi by mouth for heart disease, cancer, stomach pain, indigestion, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse wasabi with horseradish or moringa. These are not the same.
Uses
We currently have no information for Wasabi overview.
Side Effects
When taken by mouth: Wasabi is commonly consumed in foods. There isn't enough reliable information to know if wasabi is safe to use as medicine or what the side effects might be.
Precautions
When taken by mouth: Wasabi is commonly consumed in foods. There isn't enough reliable information to know if wasabi is safe to use as medicine or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if wasabi is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Bleeding disorders: Wasabi might slow blood clotting. Large amounts of wasabi might increase the risk of bleeding and bruising in people with bleeding disorders.
Surgery: Wasabi might slow blood clotting. Large amounts of wasabi might cause too much bleeding during surgery. Stop taking wasabi as a medicine at least 2 weeks before surgery.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications that slow blood clotting (Anticoagulant/Antiplatelet drugs) interacts with WasabiWasabi might slow blood clotting. Taking large amounts of wasabi along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Dosing
Wasabi is commonly consumed in foods. As medicine, there isn't enough reliable information to know what an appropriate dose might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Hou, D. X., Fukuda, M., Fujii, M., and Fuke, Y. Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl)hexyl isothiocyanate, an active principle of wasabi (Eutrema wasabi Maxim). Cancer Lett 2000;161(2):195-200.
- Nomura, T., Shinoda, S., Yamori, T., Sawaki, S., Nagata, I., Ryoyama, K., and Fuke, Y. Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro. Cancer Detect Prev 2005;29(2):155-160.
- Watanabe, M., Ohata, M., Hayakawa, S., Isemura, M., Kumazawa, S., Nakayama, T., Furugori, M., and Kinae, N. Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi. Phytochemistry 2003;62(5):733-739.
- Morimitsu, Y., Hayashi, K., Nakagawa, Y., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, wasabi. Biofactors 2000;13(1-4):271-276.
- Morimitsu, Y., Hayashi, K., Nakagawa, Y., Fujii, H., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, Wasabi. Mech Ageing Dev 2000;116(2-3):125-134.
- Yamaguchi, M. Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi 2006;126(11):1117-1137.
- Shin, I. S., Masuda, H., and Naohide, K. Bactericidal activity of wasabi (Wasabia japonica) against Helicobacter pylori. Int J Food Microbiol 2004;94(3):255-261.
- Eid SR, Crown ED, Moore EL, Liang HA, Choong KC, Dima S, Henze DA, Kane SA,Urban MO. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain 2008;4:48.
- Depree JA, Howard TM, Savage GP. Flavour and pharmaceutical properties of the volatile sulphur compounds of wasabi (Wasabia japonica). Food Res Int 1999;31(5):329-337.
- Weil, M. J., Zhang, Y., and Nair, M. G. Colon cancer proliferating desulfosinigrin in wasabi (Wasabia japonica). Nutr Cancer 2004;48(2):207-213.
- Weil, M. J., Zhang, Y., and Nair, M. G. Tumor cell proliferation and cyclooxygenase inhibitory constituents in horseradish (Armoracia rusticana) and Wasabi (Wasabia japonica). J Agric Food Chem 2005;53(5):1440-1444.
- Park BK, Chun E, Choi JJ, et al. Administration of Wasabia koreana ameliorates irritable bowel syndrome-like symptoms in a zymosan-induced mouse model. J Med Food. 2017;20(5):474-84. doi: 10.1089/jmf.2016.3844.
- Kang JH, Choi S, Jang JE, et al. Wasabia japonica is a potential functional food to prevent colitis via inhibiting the NF-κB signaling pathway. Food Funct. 2017;8(8):2865-74. doi: 10.1039/c7fo00576h.
- Hsuan SW, Chyau CC, Hung HY, Chen JH, Chou FP. The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer. Eur J Nutr. 2016;55(2):491-503. doi: 10.1007/s00394-015-0866-5.
- Choi BR, Kim HJ, Lee YJ, Ku SK. Anti-diabetic obesity effects of Wasabia Japonica Matsum leaf extract on 45% Kcal high-fat diet-fed mice. Nutrients. 2020 Sep 16;12(9):2837.
- Thomaz FS, Altemani F, Panchal SK, Worrall S, Dekker Nitert M. The influence of wasabi on the gut microbiota of high-carbohydrate, high-fat diet-induced hypertensive Wistar rats. J Hum Hypertens. 2021 Feb;35(2):170-180.
- Tanabe Y, Akazawa N, Nishimaki M, Shimizu K, Fujii N, Takahashi H. Effects of 6-(methylsulfinyl)hexyl isothiocyanate ingestion on muscle damage after eccentric exercise in healthy males: a pilot placebo-controlled double-blind crossover study. J Diet Suppl. 2021 May 3:1-15.
- Thomaz FS, Tan YP, Williams CM, Ward LC, Worrall S, Panchal SK. Wasabi (Eutrema japonicum) Reduces Obesity and Blood Pressure in Diet-Induced Metabolic Syndrome in Rats. Foods 2022;11(21):3435.
- Oka T, Yamada Y, Lkhagvasuren B, et al. Clinical effects of wasabi extract containing 6-MSITC on myalgic encephalomyelitis/chronic fatigue syndrome: an open-label trial. Biopsychosoc Med 2022;16(1):26.
- Nakajima R, Kanou M, Tokushima M, Iwama Y, Yamana K. Oral administration of 6-methylsulfinylhexyl isothiocyanate extracted from wasabi is safe and improves the fatigue and sleep of healthy volunteers. Biopsychosoc Med 2023;17(1):30.