Sweet Clover
OTHER NAME(S): Angipars, Casse Lunettes, Common Melilot, Couronne Royale, Field Melilot, Hart's Tree, Hay Flower, Herbe aux Puces, King's Clover, Luzerne Bâtarde, Melilot, Mélilot des Champs, Mélilot Commun, Mélilot Jaune, Mélilot Officinal, Mélilot Vulgaire, Meliloti Herba, Meliloto, Melilotus, Petit-Trèfle Jaune, Pratelle, Sweet Lucerne, Sweet Melilot, Tall Melilot, Thé de Jardin, Trèfle des Mouches, Wild Laburnum, Yellow Melilot, Yellow Sweet Clover, Melilotus officinalis, Sertula arvensis, Melilotus altissimus, Melilotus macrorrhizus, Trébol de Olor, Mélilot
Overview
Sweet clover (Melilotus officinalis) is a plant native to Europe and now found throughout the world. Its flowering branch and leaf are used as medicine.
Sweet clover contains ingredients that might thin the blood and help wounds heal.
People use sweet clover for varicose veins, poor blood circulation, nerve pain in people with diabetes, bruises, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse sweet clover with red clover. These are not the same.
Uses
We currently have no information for Sweet Clover overview.
Side Effects
When taken by mouth: Sweet clover is possibly safe when used appropriately. But it is possibly unsafe when used in large amounts due to the risk for liver damage and bleeding problems.
Precautions
When taken by mouth: Sweet clover is possibly safe when used appropriately. But it is possibly unsafe when used in large amounts due to the risk for liver damage and bleeding problems.
Pregnancy and breast-feeding: There isn't enough reliable information to know if sweet clover is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Liver disease: Sweet clover might make liver disease worse. If you have liver problems, speak with your healthcare provider before using sweet clover.
Surgery: Sweet clover might slow blood clotting. This might increase the risk of bleeding during or after surgery. Stop using sweet clover at least 2 weeks before a scheduled surgery.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications that can harm the liver (Hepatotoxic drugs) interacts with Sweet CloverSweet clover might harm the liver. Some medications can also harm the liver. Taking sweet clover along with a medication that can harm the liver might increase the risk of liver damage.
- Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Sweet CloverSweet clover might slow blood clotting. Taking sweet clover along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Dosing
There isn't enough reliable information to know what an appropriate dose of sweet clover might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hogan RP III. Hemorrhagic diathesis caused by drinking an herbal tea. JAMA 1983;249:2679-80.
- Tamura S, Warabi Y, Matsubara S. Severe liver dysfunction possibly caused by the combination of interferon beta-1b therapy and melilot (sweet clover) supplement. J Clin Pharm Ther 2012;37(6):724-5.
- Cornara L, Xiao J, Burlando B. Therapeutic potential of temperate forage legumes: a review. Crit Rev Food Sci Nutr 2016;56 Suppl 1:S149-61.
- Bakhshayeshi S, Madani SP, Hemmatabadi M, et al. Effects of Semelil (ANGIPARS) on diabetic peripheral neuropathy: a randomized, double-blind placebo-controlled clinical trial. Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2011;19(1):65.
- Paun G, Neagu E, Albu C, Savin S, Radu GL. In Vitro Evaluation of Antidiabetic and Anti-Inflammatory Activities of Polyphenolic-Rich Extracts from Anchusa officinalis and Melilotus officinalis. ACS Omega 2020;5(22):13014-13022.
- Hassani M, Soleimani M, Esmaeilzadeh E, Zare-Abdollahi D, Khorram Khorshid HR. Healing Influence of Melilotus Officinalis Herbal Extract on Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice. Iran J Pharm Res 2020;19(4):321-329.
- Consorti G, Monarchi G, Paglianiti M, Betti E, Balercia P. Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients. J Clin Med 2024;13(4):922.
