Sodium Tetrachloroaurate
OTHER NAME(S): EINECS 239-241-3, Gold Chloride Sodium, Gold Sodium Chloride, Hydrochloroauric Acid (Sodium Salt), Natrium Tetrachloroauratum, Sodium Chloroaurate, Sodium Gold Chloride, Sodium Gold (III) Chloride, Sodium Tetrachloroaurate (1-), Sodium Tetrachloroaurate (3+), Tetrachloroaurate (1-) Sodium, Tetrachloroauric (3+) Acid (Sodium Salt), UNII-7FT6QUT299, Tetracloroaurato Sódico
Overview
Sodium tetrachloroaurate is a gold salt.
Sodium tetrachloroaurate may be used for cancer, but there is no good scientific evidence to support this use.
In December 2019, the U.S. Food and Drug Administration added sodium tetrachloroaurate to the Dietary Supplement Ingredient Advisory List. The ingredients on this list might not be lawful to include in dietary supplements. For this reason, people may want to avoid using supplements containing sodium tetrachloroaurate.
Sodium tetrachloroaurate might reduce inflammation (swelling). It might also kill cancer cells.
Sodium tetrachloroaurate might reduce inflammation (swelling). It might also kill cancer cells.
Uses
Insufficient Evidence for
- Cancer.
- Other conditions.
Side Effects
When taken by mouth: There isn't enough reliable information to know if sodium tetrachloroaurate is safe or what the side effects might be. But sodium tetrachloroaurate is a gold salt and might cause side effects similar to other gold salts. These may include liver or kidney injury, diarrhea, loose stools, inflammation of the digestive tract, and other side effects.
When given as a shot: There isn't enough reliable information to know if sodium tetrachloroaurate is safe or what the side effects might be. But sodium tetrachloroaurate is a gold salt and might cause side effects similar to other gold salts. Common side effects of other gold salts when given as a shot are skin irritation, skin itch, and swelling of the mouth and lips. Other side effects may include liver injury, kidney injury, and discoloration of the skin.
Precautions
When taken by mouth: There isn't enough reliable information to know if sodium tetrachloroaurate is safe or what the side effects might be. But sodium tetrachloroaurate is a gold salt and might cause side effects similar to other gold salts. These may include liver or kidney injury, diarrhea, loose stools, inflammation of the digestive tract, and other side effects.
When given as a shot: There isn't enough reliable information to know if sodium tetrachloroaurate is safe or what the side effects might be. But sodium tetrachloroaurate is a gold salt and might cause side effects similar to other gold salts. Common side effects of other gold salts when given as a shot are skin irritation, skin itch, and swelling of the mouth and lips. Other side effects may include liver injury, kidney injury, and discoloration of the skin.
Pregnancy: Sodium tetrachloroaurate is POSSIBLY UNSAFE when taken by mouth or given as a shot during pregnancy. Sodium tetrachloroaurate might harm the fetus or increase the chance of miscarriage.
Breast-feeding: There isn't enough reliable information to know if sodium tetrachloroaurate is safe to use when breast-feeding. Gold from sodium tetrachloroaurate might be excreted into breastmilk. It's unclear if this will harm the baby. Stay on the safe side and avoid use.
Interactions
We currently have no information for Sodium Tetrachloroaurate overview.
Dosing
The appropriate dose of sodium tetrachloroaurate depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for sodium tetrachloroaurate. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- U.S. Food & Drug Administration. Dietary supplement ingredient advisory list. https://www.fda.gov/food/dietary-supplement-products-ingredients/dietary-supplement-ingredient-advisory-list. Accessed December 17, 2019.
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- Suwalsky M, Zambenedetti P, Carpené E, et al. Effects of chronic treatment with sodium tetrachloroaurate(III) in mice and membrane models. J Inorg Biochem. 2004;98(12):2080-6.
- Ridaura (auranofin) [package insert]. San Diego, CA: Prometheus Laboratories, Inc; 2011.
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Gold Preparations. [Updated 2017 Aug 2].
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- Merchant B. Gold, the noble metal and the paradoxes of its toxicology. Biologicals. 1998;26(1):49-59.
- Nobili S, Mini E, Landini I, et al. Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies. Med Res Rev. 2010;30(3):550-80.
- Saito S, Okabe M, Kurasaki M. Localization of renal Cu-binding metallothionein induced by Au injection into rats. Biochim Biophys Acta. 1997;1335(3):353-8.
