Securinega Suffruticosa

OTHER NAME(S): Flueggea suffruticosa, Hitotsuba-hagi, Pharnaceum suffruticosum, Securinega, Securinega ramiflora, Securinega suffruticosa, Flueggea suffruticosa, Securinega ramiflora, Pharnaceum suffruticosum

Overview

Securinega suffruticosa is an herb that is used in traditional Chinese medicine (TCM). Its red-brown fruits and leaves are considered edible.

Securinega suffruticosa contains a chemical that can act like a stimulant in the body.

People use Securinega suffruticosa for heartburn, bruising, back pain, multiple sclerosis (MS), and many other conditions, but there is no good scientific evidence to support these uses.

References
  1. Securinega suffruticosa - (Pall.)Rehder. Plants for a Future. [Accessed January 3, 2016]. Available at: https://www.pfaf.org/User/Plant.aspx?LatinName=Securinega+suffruticosa
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  3. Li M, Han S, Zhang G, Wang Y, Ji Z. Antiproliferative activity and apoptosis-inducing mechanism of L-securinine on human breast cancer MCF-7 cells. Pharmazie. 2014;69(3):217-23.
  4. Lin TJ, Su CC, Lan CK, et al. Acute poisonings with Breynia officinalis--an outbreak of hepatotoxicity. J Toxicol Clin Toxicol. 2003;41(5):591-4.
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  7. Zhang G, Li M, Han S, et al. Induction of human chronic myeloid leukemia K562 cell apoptosis by virosecurinine and its molecular mechanism. Mol Med Rep. 2014;10(5):2365-71.
  8. Zhang J, Yao J, Peng S, Li X, Fang J. Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase. Biochim Biophys Acta. 2017;1863(1):129-138.
  9. Zhou L, Zhao BX, Jiang RW, et al. Securinega alkaloids from the fruits of Flueggea suffruticosa. J Asian Nat Prod Res. 2014;16(6):593-601.
  10. Han BH, Song CH, Yoon JJ, et al. Anti-Vascular Inflammatory Effect of Ethanol Extract from Securinega suffruticosa in Human Umbilical Vein Endothelial Cells. Nutrients 2020;12(11):3448.