Rice Protein
OTHER NAME(S): Extensively Hydrolyzed Rice Protein, Extensive Rice Hydrolysate, Hydrolyzed Rice Bran Protein, Hydrolyzed Rice Protein, Partial Rice Hydrolysate, Partially Hydrolyzed Rice Protein, Rice Bran Protein, Rice Endosperm Protein, Rice Protein Hydrolysate, Rice Protein Isolate, Proteína del arroz, Protéine de riz
Overview
Rice protein is protein that has been taken from rice. Sometimes it is broken down into smaller pieces. Rice protein that is broken down into smaller pieces is called rice protein hydrolysate.
Rice protein is taken by mouth for muscle strength and muscle soreness. It is also used in infant formulas for babies who are allergic to cow's milk.
Rice protein is used in skin and hair products.
Rice protein provides the body with nutrients called amino acids. The kinds of amino acids in rice protein might help to protect the body from too much sugar in the blood. They might also help to reduce blood pressure and blood fats.
Rice protein provides the body with nutrients called amino acids. The kinds of amino acids in rice protein might help to protect the body from too much sugar in the blood. They might also help to reduce blood pressure and blood fats.
Uses
Possibly Effective for
- Food allergies. Most infant formulas are made with protein that comes from cow's milk. If an infant is allergic to cow's milk, a special form of cow's milk formula can be used instead. But this type of formula often tastes bitter. Most research shows that rice protein formulas can be a good protein replacement for these babies. When rice protein is used in formula, it is broken down into smaller pieces and some additional nutrients are added to make it a complete source of nutrition for infants.
Insufficient Evidence for
- Muscle soreness caused by exercise. Early research shows that taking rice protein in water immediately after exercise works as well as whey protein for reducing muscle soreness after exercise.
- Muscle strength. Early research shows that taking rice protein in water immediately after exercise works as well as whey protein for building muscle strength.
Side Effects
When taken by mouth: Rice protein is POSSIBLY SAFE when used as an ingredient in foods.
When applied to the skin: Rice protein is POSSIBLY SAFE.
Precautions
When taken by mouth: Rice protein is POSSIBLY SAFE when used as an ingredient in foods.
When applied to the skin: Rice protein is POSSIBLY SAFE.
Children: Rice protein is POSSIBLY SAFE when used orally by children 1 month of age and older. It has been used safely as a special form of infant formula by infants who are allergic to cow's milk. But some infants can be allergic to rice protein, so this type of formula should only be used under the supervision of a healthcare professional.
Rice contains inorganic arsenic, which can be unsafe in large amounts. Look for products that include the amount of arsenic on the label.
Pregnancy and breast-feeding: There isn't enough information to know if rice protein is safe to use when pregnant or breast-feeding. Stay on the safe side and only use amounts found in food.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications for high blood pressure (ACE inhibitors) interacts with Rice proteinRice protein inhibits a chemical called ACE in the body. Medications called ACE inhibitors are used to decrease blood pressure. Taking rice protein along with these medications called ACE inhibitors might cause your blood pressure to go too low. Some ACE inhibitors include benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik).
Dosing
BY MOUTH:
- For food allergies: Infant formula containing rice protein and other nutrients has been used as the only source of food for infants between 1-6 months of age. It has been used along with other foods in children between 6 months and 2 years of age.
References
- Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J 2013;12:86.
- Li GH, Qu MR, Wan JZ, You JM. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr. 2007;16 Suppl 1:275-80.
- Hojsak I, Braegger C, Bronsky J, ESPGHAN Committee on Nutrition; et al. Arsenic in rice: a cause for concern. J Pediatr Gastroenterol Nutr. 2015;60(1):142-5.
- Vandenplas Y, De Greef E, Paradice Study Group. An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month. Arch Dis Child. 2014;99(10):933-6.
- Vandenplas Y, De Greef E, Paradice Study Group. Safety and tolerance of a new extensively hydrolyzed rice protein-based formula in the management of infants with cow's milk protein allergy. Eur J Pediatr. 2014;173(9):1209-16.
- Kubota M, Watanabe R, Kabasawa H, et al. Rice protein ameliorates the progression of diabetic nephropathy in Goto-Kakizaki rats with high-sucrose feeding. Br J Nutr. 2013;110(7):1211-9.
- Reche M, Pascual C, Fiandor A, et al. The effect of a partially hydrolysed formula based on rice protein in the treatment of infants with cow's milk protein allergy. Pediatr Allergy Immunol. 2010;21(4 Pt 1):577-85.
- Lasekan JB, Koo WW, Walters J, Neylan M, Luebbers S. Growth, tolerance and biochemical measures in healthy infants fed a partially hydrolyzed rice protein-based formula: a randomized, blinded, prospective trial. J Am Coll Nutr. 2006;25(1):12-9.
- Urisu A, Yamada K, Masuda S, et al. 16-kilodalton rice protein is one of the major allergens in rice grain extract and responsible for cross-allergenicity between cereal grains in the Poaceae family. Int Arch Allergy Appl Immunol. 1991;96(3):244-52.
- Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice) germ oil, rice bran acid, Oryza sativa (rice) bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sativa (rice) germ powder, Oryza sativa (rice) starch, Oryza sativa (rice) bran, hydrolyzed rice bran extract, hydrolyzed rice bran protein, hydrolyzed rice extract, and hydrolyzed rice protein. Int J Toxicol. 2006;25 Suppl 2:91-120.
- Liu CK, Chen CA, Lee TY, Chang HH, Liao HF, Chen YJ. Rice protein prolamin promotes anti-leukemia immunity and inhibits leukemia growth in vivo. Food Chem Toxicol. 2018;112:435-440.
- Zhang C, Zhang R, Li YM, et al. Cholesterol-lowering activity of tartary buckwheat protein. J Agric Food Chem. 2017;65(9):1900-1906.
- Ishikawa Y, Hira T, Inoue D, et al. Rice protein hydrolysates stimulate GLP-1 secretion, reduce GLP-1 degradation, and lower the glycemic response in rats. Food Funct. 2015;6(8):2525-34.
- Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
- Yang L, Han G, Liu QH, et al. Rice protein exerts a hypocholesterolemic effect through regulating cholesterol metabolism-related gene expression and enzyme activity in adult rats fed a cholesterol-enriched diet. Int J Food Sci Nutr. 2013;64(7):836-42.
- Um MY, Ahn J, Jung CH, Ha TY. Cholesterol-lowering effect of rice protein by enhancing fecal excretion of lipids in rats. Prev Nutr Food Sci. 2013;18(3):210-3.
- Burris RL, Xie CH, Thampi P, Wu X, Melnyk SB, Nagarajan S. Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes. Atherosclerosis. 2010;212(1):107-15.
- Yu S, Fang N, Li Q, et al. In vitro actions on human cancer cells and the liquid chromatography-mass spectrometry/mass spectrometry fingerprint of phytochemicals in rice protein isolate. J Agric Food Chem. 2006;54(12):4482-92.
- Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6.
- https://www.accessdata.fda.gov/scripts/fdcc/?set=GRASNotices&id=609&sort=GRN_No&order=DESC&startrow=1&type=basic&search=rice%20protein. Accessed Nov. 27, 2018.