Maral Root
OTHER NAME(S): Leuzea, Lou Cao, Maralrot, Lou Cao, Raíz de Maral, Racine de Maral, Saflor Bergscharte, Rhaponticum carthamoides, synonyms Cnicus carthamoides, Leuzea carthamoides, Stemmacantha carthamoides, Raíz De Maral, Racine De Maral
Overview
Maral root is part of a plant. The roots are used to make medicine.
People use maral root for athletic performance, depression, sexual problems that prevent satisfaction during sexual activity, and many other conditions, but there is no good scientific evidence to support these uses.
There isn't enough reliable information available to know how maral root might work.
There isn't enough reliable information available to know how maral root might work.
Uses
Insufficient Evidence for
- Athletic performance.
- Depression.
- Conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility).
- Parasites.
- Sexual problems that prevent satisfaction during sexual activity.
- Other conditions.
More evidence is needed to rate the effectiveness of maral root for these uses.
Side Effects
When taken by mouth: There isn't enough reliable information to know if maral root is safe or what the side effects might be.
Precautions
When taken by mouth: There isn't enough reliable information to know if maral root is safe or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if maral root is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Allergy to ragweed and related plants: Maral root may cause an allergic reaction in people who are allergic to the Asteraceae/Compositae plant family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking maral root.
Bleeding disorders: Maral root might slow blood clotting. In theory, maral root might increase the risk of bruising and bleeding in people with bleeding disorders.
Surgery: Maral root might slow blood clotting. There is concern that it might increase the risk of bleeding during and after surgery. Stop using maral root at least 2 weeks before a scheduled surgery.
Interactions
Moderate Interaction
Be cautious with this combination
- Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Maral RootMaral root might slow blood clotting. Taking maral root along with medications that also slow clotting might increase the chances of bruising and bleeding. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others.
Dosing
The appropriate dose of maral root depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for maral root. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Shukla A, Rasik AM, Jain GK, et al. In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. J Ethnopharmacol 1999;65:1-11.
- Kokoska L, Polesny Z, Rada V, et al. Screening of some Siberian medicinal plants for antimicrobial activity. J Ethnopharmacol 2002;82:51-3.
- Kokoska L, Janovska D. Chemistry and pharmacology of Rhaponticum carthamoides: a review. Phytochemistry 2009;70(7):842-55.
- Budesinsky M, Vokac K, Harmatha J, Cvacka J. Additional minor ecdysteroid components of Leuzea carthamoides. Steroids 2008;73(5):502-14.
- Sovova H, Opletal L, Sajfrtova M, Bartlova M. Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC. J Sep Sci 2008;31(8):1387-92.
- Miliauskas G, van Beek TA, de Waard P, et al. Identification of radical scavenging compounds in Rhaponticum carthamoides by means of LC-DAD-SPE-NMR. J Nat Prod 2005;68(2):168-72.
- Stodulka P, Koleckar V, Jun D, et al. High-performance liquid chromatography analysis of four Leuzea carthamoides flavonoids. J Chromatogr Sci 2008;46(2):162-4.
- Koleckar V, Opletal L, Brojerova E, et al. Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae. J Enzyme Inhib Med Chem 2008;23(2):218-24.
- Chobot V, Vytlacilova J, Kubicova L, et al. Phototoxic activity of a thiophene polyacetylene from Leuzea carthamoides. Fitoterapia 2006;77(3):194-8.
- Szendrei K, Reisch J, Erzsebet V. Thiophene acetylenes from Leuzea roots. Phytochemistry 1984;23(4):901-2.
- Chobot V, Buchta V, Jahodarova H, et al. Antifungal activity of a thiophene polyine from Leuzea carthamoides. Fitoterapia 2003;74(3):288-90.
- Havlik J, Budesinsky M, Kloucek P, et al. Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil. Phytochemistry 2009;70(3):414-8.
- Slama K, Koudela K, Tenora J, Mathova A. Insect hormones in vertebrates: anabolic effects of 20-hydroxyecdysone in Japanese quail. Experientia 1996;52(7):702-6.
- Gaube F, Wolfl S, Pusch L, et al. Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays. Planta Med 2008;74(14):1701-8.
- Koleckar V, Brojerova E, Rehakova Z, et al. In vitro antiplatelet activity of flavonoids from Leuzea carthamoides. Drug Chem Toxicol 2008;31(1):27-35.
- Kuz'menko AI, Morozova RP, Nikolenko IA, Donchenko GV. Antioxidant effect of 20-hydroxyecdysone in a model system. Ukr Biokhim Zh (1999) 1999;71(3):35-8.
- Plotnikov MB, Aliev OI, Vasil'ev AS, et al. Effect of Rhaponticum carthamoides extract on structural and metabolic parameters of erythrocytes in rats with cerebral ischemia. Bull Exp Biol Med 2008;146(1):45-8.
- Logvinov SV, Pugachenko NV, Potapov AV, et al. Ischemia-induced changes in synaptoarchitectonics of brain cortex and their correction with ascovertin and Leuzea extract. Bull Exp Biol Med 2001;132(4):1017-20.
- Roumanille R, Vernus B, Brioche T, et al. Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats. J Int Soc Sports Nutr 2020;17(1):58.
- Ryan ED, Gerstner GR, Mota JA, et al. The Acute Effects of a Multi-Ingredient Herbal Supplement on Performance Fatigability: A Double-Blind, Randomized, and Placebo-Controlled Trial. J Diet Suppl 2021;18(5):507-516.
