Divi-Divi
OTHER NAME(S): Bagore, Bonduc, Bonduc Nut, Canique Grise, Cascalote, Divi Divi, Dividivi, Fever Nut, Gray Nicker, Ka-Lain, Lata Karanj, Latakaranj, Moluca Bean, Nacascolo, Nichol Seeds, Nicker Nut, Nikkar Nuts, Putikaranja, Sagar Ghota, Sagar Gota, Teri Pods, Udakiryaka, Z'yeux à Chatte, Caesalpinia bonduc, Caesalpinia bonducella, Caesalpinia crista, Guilandina bonduc, Guilandina bonducella, Canique grise
Overview
Divi-divi (Caesalpinia bonduc) is a large shrub with thorny leaves. It grows in various countries where its seeds and leaves have been used to make medicine.
Ingredients in the divi-divi seeds might have activity against malaria, bacteria, and parasites.
People take divi-divi for malaria, fever, diabetes, infection of the intestines by parasites, and other conditions, but there is no good scientific evidence to support these uses.
Uses
We currently have no information for Divi-Divi overview.
Side Effects
When taken by mouth: There isn't enough reliable information to know if divi-divi is safe or what the side effects might be.
Precautions
When taken by mouth: There isn't enough reliable information to know if divi-divi is safe or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if divi-divi is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
We currently have no information for Divi-Divi overview.
Dosing
There isn't enough reliable information to know what an appropriate dose of divi-divi might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
References
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Sharma SR, Dwivedi SK, Swarup D. Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. J Ethnopharmacol 1997;58:39-44.
- Kalauni SK, Awale S, Tezuka Y, et al. Antimalarial activity of cassane- and norcassane-type diterpenes from Caesalpinia crista and their structure-activity relationship. Biol Pharm Bull. 2006;29(5):1050-2.
- Saeed MA, Sabir AW. Antibacterial activity of Caesalpinia bonducella seeds. Fitoterapia. 2001;72(7):807-9.
- Simin K, Khaliq-Uz-Zaman SM, Ahmad VU. Antimicrobial activity of seed extracts and bondenolide from Caesalpinia bonduc (L.) Roxb. Phytother Res. 2001;15(5):437-40.
- Iftikhar A, Aslam B, Iftikhar M, et aI. Effect of Caesalpinia bonduc polyphenol extract on alloxan-induced diabetic rats in attenuating hyperglycemia by upregulating insulin secretion and inhibiting JNK signaling pathway. Oxid Med Cell Longev. 2020 Mar 17;2020:9020219.
- Kousar S, Aslam B, Muhammad F, Khan JA. Hepatoprotective and hypolipidemic activities of Caesalpinia bonduc seed kernels and Gymnema sylvestre leaves extracts in alloxan-induced diabetic rats. Pak J Pharm Sci. 2021 Jan;34(1(Supplementary)):307-11.
- Sindete M, Rharass T, Gbankoto A, et al. A comparative study of Caesalpinia bonduc (L.) Roxb. root extracts on sexual behaviour in male Wistar rats. Andrologia. 2021 Aug;53(7):e14072.