Cade
OTHER NAME(S): Alquitran de Enebro, Cada, Cade Essential Oil, Cade Juniper, Cade Leaf, Cade Oil, Cade Stem, Cade Wood, Cade Wood Essential Oil, Cade Wood Oil, Common Juniper, Essence de Cade, Feuille de Cade, Genévrier Cade, Genévrier Epineux, Genévrier Oxycèdre, Goudron de Cade, Huile de Cade, Huile Essentielle de Cade, Juniper Tar, Juniper Tar Oil, Kade, Kadeoel, Kade Oil, Oil of Cade, Oil of Juniper Tar, Oleum Cadinum, Oleum Juniperi Empyreumaticum, Oxycèdre, Pix Cadi, Pix Juniper, Pix Oxycedri, Plum Juniper, Prickly Cedar, Prickly Juniper, Pyroleum Juniperi, Pyroleum Oxycedri, Rectified Cade Oil, Red-Berry Juniper, Sharp Cedar, Wacholderteer, Juniperus oxycedrus
Overview
Cade is a plant. The leaf, berries, stem, and oil extracted from the wood are used for medicine. The oil is also commonly used as a fragrance in perfumes, skin creams, and other products.
Cade oil is taken by mouth or applied to the skin for many different conditions, but there is no good scientific evidence to support these uses. Using cade can also be unsafe.
Some studies in the lab show that cade extracts can kill bacteria, decrease swelling (inflammation), and improve blood sugar levels. There isn't enough information to know if cade has these effects in people.
Some studies in the lab show that cade extracts can kill bacteria, decrease swelling (inflammation), and improve blood sugar levels. There isn't enough information to know if cade has these effects in people.
Uses
Insufficient Evidence for
- Diabetes.
- Diarrhea.
- Peptic ulcer disease (PUD).
- High blood pressure.
- Lung infections.
- Common cold.
- Kidney stones.
- Cancer.
- Psoriasis.
- Eczema.
- Scabies.
- Wounds.
- Head lice.
- Dandruff.
- Hair loss.
- Cancers.
- Snake bites.
- Other conditions.
More evidence is needed to rate the effectiveness of cade for these uses.
Side Effects
When taken by mouth: Fully processed cade oil ("rectified cade oil") is POSSIBLY UNSAFE. It irritates the lining of the mouth and can cause serious side effects such as breathing problems, organ failure, seizures, and coma. Cade oil that has not been fully processed to remove cancer-causing compounds is LIKELY UNSAFE. Avoid using any form of cade oil by mouth.
When applied to the skin: Fully processed cade oil ("rectified cade oil") is LIKELY SAFE when applied to the skin in preparations containing 1% to 5% of the oil. These products seem to be safe to use short-term for minor skin problems. But cade oil that has not been fully processed to remove cancer-causing compounds is LIKELY UNSAFE to apply to the skin. Avoid using it.
There isn't enough reliable information to know if taking cade berries or leaf extracts is safe or what the side effects might be.
Precautions
When taken by mouth: Fully processed cade oil ("rectified cade oil") is POSSIBLY UNSAFE. It irritates the lining of the mouth and can cause serious side effects such as breathing problems, organ failure, seizures, and coma. Cade oil that has not been fully processed to remove cancer-causing compounds is LIKELY UNSAFE. Avoid using any form of cade oil by mouth.
When applied to the skin: Fully processed cade oil ("rectified cade oil") is LIKELY SAFE when applied to the skin in preparations containing 1% to 5% of the oil. These products seem to be safe to use short-term for minor skin problems. But cade oil that has not been fully processed to remove cancer-causing compounds is LIKELY UNSAFE to apply to the skin. Avoid using it.
There isn't enough reliable information to know if taking cade berries or leaf extracts is safe or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if cade is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Children: Any preparations containing cade oil are LIKELY UNSAFE for children, either taken by mouth or when applied to the skin. Children seem to be at higher risk for serious, even deadly reactions to cade oil.
Cypress allergy: Pollen from cade trees can cause allergic reactions in people with cypress allergies.
Interactions
We currently have no information for Cade overview.
Dosing
The appropriate dose of cade depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cade. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
References
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- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Prudden JF, Balassa LL. The biological activity of bovine cartilage preparations. Clinical demonstration of their potent anti-inflammatory capacity with supplementary notes on certain relevant fundamental supportive studies. Semin Arthritis Rheum 1974;3:287-321.
- Anon. Final report on the safety assessment of Juniperus communis Extract, Juniperus oxycedrus Extract, Juniperus oxycedrus Tar, Juniperus phoenicea extract, and Juniperus virginiana Extract. Int J Toxicol 2001;20:41-56.
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- Orhan N, Aslan M, Demirci B, Ergun F. A bioactivity guided study on the antidiabetic activity of Juniperus oxycedrus subsp. oxycedrus L. leaves. J Ethnopharmacol 2012;140(2):409-15.
- Orhan N, Aslan M, Pekcan M, et al. Identification of hypoglycaemic compounds from berries of Juniperus oxycedrus subsp. oxycedrus through bioactivity guided isolation technique. J Ethnopharmacol 2012;139(1):110-8.
- Achour S, Abourazzak S, Mokhtari A, et al. Juniper tar (cade oil) poisoning in new born after a cutaneous application. BMJ Case Reports 2011 Oct 28;2011.
- Hanène M, Ameur E, Larbi KM, et al. Chemical composition of the essential oils of the berries of Juniperus oxycedrus L. ssp. rufescens (L. K.) and Juniperus oxycedrus L. ssp. macrocarpa (S. & m.) Ball. and their antioxidant activities. Nat Prod Res 2012;26(9):810-20.
- Skalli S, Chebat A, Badrane N, Bencheikh RS. Side effects of cade oil in Morocco: an analysis of reports in the Moroccan herbal products database from 2004 to 2012. Food Chem Toxicol 2014;64:81-5.
- Taviano MF, Marino A, Trovato A, et al. Juniperus oxycedrus L. subsp. oxycedrus and Juniperus oxycedrus L. subsp. macrocarpa (Sibth. & Sm.) Ball. "berries" from Turkey: comparative evaluation of phenolic profile, antioxidant, cytotoxic and antimicrobial activities. Food Chem Toxicol 2013;58:22-9.
- Tavares L, McDougall GJ, Fortalezas S, et al. The neuroprotective potential of phenolic-enriched fractions from four Juniperus species found in Portugal. Food Chem 2012;135(2):562-70.
- Taviano MF, Marino A, Trovato A, et al. Antioxidant and antimicrobial activities of branches extracts of five Juniperus species from Turkey. Pharm Biol 2011;49(10):1014-22.
- Rahmani H, Leonhardt S, Beladdale D, et al. Severe acute lung oedema after rectal enema with cade oil (abstract). European Association of Poisons Centres and Clinical Toxicologists XXIV International Congress, Strasbourg, 2004. Clin Toxicol 2004;42(4):487.
- Code of Federal Regulations, Title 21, chapter 1, subchapter D, part 346, subpart B (21CFR346.16). Anorectal drug products for over-the-counter human use - Analgesic, anesthetic, and antipruritic active ingredients.
